Cephalosporin Flashcards
ALL BETA LACTAMS including cephalosporins are bacteri__.
bactericidal
Which are the species that are resistant to Cephalosporin?
Listeria monocytogenes Atypicals(mycoplasma and chlamydia included? MRSA(Except 5th generation) Enterococci LAME
Which is the most commonly used first generation cephalosporin?
Cefazolin
1G CEPHALOSPORİNS –>PEK PSS
Proteus E.coli Klebsiella Pneumococci Streptococci Staphylococcus aureus
–>activities greater on gram+/-?
1G
2G
3G
1G–>greater activity on gram + aerobes
2G–> greater activity on gram - aerobes
3G–>gram - more resistant to beta lactamases,more active against Pseudomonas
Cephalosporins are ___ resistant to beta lactamases than penicillin
more
2G cephalosporins HENPEK?
H.influenza Enterobacter Neisseria Proteus.mirebilis E.coli K.Pneumoniae
Which of the two have longest half life of all cephalosporins?
Ceftriaxone
Which cephalosporins are excreted via bile?
Ceftriaxone and Cefoperazone
What are the common side effects of cephalosporins?
DDTHAPNS
DİARRHEA DİSULFİRAM LİKE RXN THROMBOPHLEBİTİS HYPOPROTHROMBİNEMİA ALLERGY PAİN NEPHROTOXİCİTY SUPER İNFECTİONS
What is the route of administration for cephalosporins?
Parenteral
WHAT ARE THE ANTİPSEUDOMONAL CEPHALOSPORİNS?
.Cefoperazone
.Ceftazidime
.Cefepime
.5th G
5G Cephalosporins?
Ceftobiprole
Ceftaroline
When do we use 5G cephalosporins especially?
When there are methicillin resistant strains
What are the species that we use 5G antibiotics for?
Methicillin resistant Staphylococcus aureus and E.faecalis
