Basic properties of antimicrobial chemotherapeutics

Question 1

Bactericidal&Inhibitor of cell wall synthesis

Answer 1

Penicillins
Cephalosporins
Cycloserine
Vancomycin
Bacitracin

Question 2

Antifungal&inhibits cell wall synthesis

Answer 2

Miconazole
Ketaconazole
Clotrimazole

Question 3

Increase in plasma membrane permaebility&Bactericidal

Answer 3

Polymyxin

Colisthimthate

Question 4

Increase in plasma membrane permaebility&Antifungal

Answer 4

Nystatin

Amphotericin B

Question 5

Disrupt function of protein synthesis via 30S 50S&Bacteriostatic

Answer 5

Chloramphenicol
Tetracyclin
Erythromycin
Climdamycin
Linezolid

Question 6

Disrupt function of protein synthesis via 30S 50S&Bactericidal

Answer 6

AMİNOGLYCOSİDES

Question 7

Inhibition of DNA dependent RNA polymerase bactericidal

Answer 7

Rifamycins

Question 8

Inhibition of supercoiling&Dna synthesis(- topoisomerase) bactericidal

Answer 8

Quinolones

Question 9

What is antibiotic susceptibility test in vitro?

Answer 9

Agar disk diffusion

Question 10

What is the purpose of AGAR DİSK DİFFUSİON

Answer 10

Calculating MIC(inversely related w diameter of zone)

Question 11

What is FIC index?

Answer 11

Used for calculating activities of combined therapies.

Question 12

What does it mean FIC İNDEX>1
=1
<1

Answer 12

antagonisim btw two drugs
addition
synergism

Question 13

What is FUO?

Answer 13

It is fever persisting more than 2 weeks
%25 infectious related (tuberculosis,fungi usually)
%75 noninfectious related
so dont give every fuo antibiotic bcs only 1/4 is infectious related