Central Nervous System Drugs

Question 1

It impedes the entry of drugs into the brain and protects the brain from injury by potentially toxic substances, but it can also be a significant
obstacle to entry of therapeutic agents

Answer 1

BLOOD-BRAIN BARRIER

Question 2

It refers to the decreased response occurring in the course of prolonged drug use

Answer 2

TOLERANCE

Question 3

It refers to
a state in which abrupt discontinuation of drug use will precipitate a withdrawal syndrome.

Answer 3

PHYSICAL DEPENDENCE

Question 4

TRUE OR FALSE:
Do not abruptly discontinue the use of all cns medication to prevent induction of seizure

Answer 4

TRUE

Question 5

This condition is due to dysregulation of the transmitter serotonin, norepinephrine, and dopamine that causes attention difficulties, hyperactivity, and inability to concentrate

Answer 5

ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)

Question 6

This condition refers toapersistentsleepconditionmarkedbyextremedaytimesleepinessand sporadicsleepepisodes.

Answer 6

NARCOLEPSY

Question 7

TRUE OR FALSE:
Give 5L of oxygen for patients with COPD

Answer 7

FALSE:
More than 3L of oxygen can risk patients with COPD for losing respiratory drive

Question 8

TRUE OR FALSE:
Administer levodopa together with carbidopa in treating parkinson’s disease

Answer 8

TRUE:
Carbidopa prevents levodopa from being converted into dopamine in the bloodstream. This allows more of the drug to get to the brain.

Question 9

TRUE OR FALSE:
Administering levodopa together with MAOI for patients with parkinson’s disease

Answer 9

FALSE:
Levodopa + MAOI = Hypertensive crisis

Question 10

TRUE OR FALSE:
Let the patient to walk around after administrating dopaminergic drugs

Answer 10

FALSE:
Dopaminergic drugs has an adverse effect that causes orthostatic hypotension that increases injury to the patient due to fall.

Question 11

TRUE OR FALSE:
If an adverse reaction occurs, notify the physician first before withholding the dose

Answer 11

FALSE:
Withhold the those then notify the physician

Question 12

TRUE OR FALSE:
Minister phenytoin to D5W because precipitate may occur instead, clear tubing first with PNSS

Answer 12

TRUE

Question 13

TRUE OR FALSE:
Health educate the patient to drink grapefruit juice after administering carbamazepine to increase the effect of the drug

Answer 13

FALSE:
Do not drink grapefruit juice as it can increase levels of the carbamazepine that leads into drug toxicity

Question 14

TRUE OR FALSE:
Do not administer carbamazepine for patients with leukopenia anemia and thrombocytopenia

Answer 14

TRUE:
Carbamazepine may decrease the number of blood cells produced by your body.

Question 15

TRUE OR FALSE:
Diazepam is not recommended for long-term use due to high potential for addiction

Answer 15

TRUE

Question 16

TRUE OR FALSE:
Administer the first dose of GABApentin at daytime to minimize effect of drowsiness, dizziness, fatigue, and ataxia

Answer 16

FALSE:
Should be at bedtime

Question 17

TRUE OR FALSE:
In administrating centrally acting agents for muscle spasm, prepare scription for mild analgesics to relieve drug-induced headache

Answer 17

TRUE

Question 18

TRUE OR FALSE:
Never give disulfiram to a patient in a state of alcohol intoxication or 12 hours after drinking alcohol

Answer 18

TRUE:
Disulfiram produces very unpleasant side effects (such as fast heartbeat, chest pain, nausea, dizziness, flushing, and thirst) when combined with alcohol in the body.

Question 19

TRUE OR FALSE:
Levodopa directly activates dopamine receptors

Answer 19

FALSE:
Levodopa metabolizes in brain to produce dopamine

Question 20

True or FALSE:
Traditional anticonvulsants can harm developing fetus during first trimester

Answer 20

TRUE