Autonomic Nervous System Drugs Flashcards
TRUE OR FALSE
All postganglionic neurotransmitter of Autonomic Nervous System are Acetylcholine
FALSE
- the postganglionic neurotransmitter of sympathetic nervous system is norepinephrine
- the postganglionic neurotransmitter of parasympathetic nervous system is acetylcholine
What are the five stages of synaptic transmission
Synthesis
Storage
Release
Action on receptor sites
Termination
It is a non catecholamine adrenergic agonist DRUG that can reduce
airway resistance in asthma by causing β₂-mediated bronchodilation through aerosol
ALBUTEROL
Atropine is an anti muscarinic agent use to treat bradycardia and reduce salivation and bronchial secretion before surgery. TRUE OR FALSE: Atropine is safe for patients with glaucoma
FALSE:
This drug is a first-generation beta blocker, produces nonselective beta blockade; blocks both β₁- and β₂-adrenergic
receptor and all of the applications of this drug are based on
blockade of β₁ receptors in the heart
indications such as hypertension, angina pectoris, cardiac dysrhythmias, and myocardial infarction.
PROPRANOLOL
Metoprolol produces selective
blockade of beta1 receptors in the heart and primary indicated for hypertension but
also approved for angina pectoris, heart failure, and myocardial infarction. Propranolol blocks both β₁ and β₂ adrenergic receptor with the same indications as metoprolol. TRUE OR FALSE: Propranolol is safer for patients with asthma than Metoprolol.
FALSE:
This DRUG has a dose-dependent receptor specificity primarily indicated with shock, heart failure by improvinh cardiac tissue perfusion and renal perfusion
DOPAMINE
The most serious adverse response to alpha-adrenergic
blockers is this hypotension that can reduce blood flow to the brain,
causing dizziness, light-headedness, and even syncope (fainting).
ORTHOSTATIC HYPOTENSION
Tamsulosin is an alpha1-adrenergic antagonist that causes “selective”
blockade of alpha1 receptors on smooth muscle of the bladder neck (trigone
and sphincter), prostatic capsule, and prostatic urethra; blockade of vascular
alpha1 receptors is weak. The is not useful
for hypertension and only approved for ________ to increase urine flow rate
and decreases residual urine volume for men
BENIGN PROSTATIC HYPERPLASIA
It is a selective α₁-agonist DRUG that
can be administered orally to reduce nasal congestion, parenterally
to elevate blood pressure, eye drops
to dilate the pupil, and also used to delay anesthetic absorption
PHENYLEPHRINE
It is a non-selective alpha and beta receptor catecholamine DRUG and able to treat cardiac arrest by restoring cardiac function, asthma for bronchodilation effects, and anaphylaxis or anaphylactic shock by reducing the effects of allergic reaction.
EPINEPHRINE
These ANS drugs produce their effects by activating adrenergic receptors
AGONISTS
It is a competitive antagonist DRUG
that produces selective blockade of alpha1-adrenergic receptors indicated for hypertension by dilating of arterioles and veins but can also benefit men with benign prostatic hyperplasia by relaxation of smooth muscle in the bladder neck and prostatic capsule
PRAZOSIN
These molecules has a benzene
ring that has hydroxyl groups on two adjacent carbons and
ethylamine on their structural formulas.
CATECHOLAMINES
Which of the following is not an effect of nicotinic receptor agonist?
a. hypertension
b. diarrhea
c. bronchodilation
d. body relaxation
C.
