Central Nervous System Drugs

Question 1

It is used for psychiatric disorders, suppression of seizures, relief of pain, and production of anesthesia.

Answer 1

Central Nervous System Drugs (CNS)

Question 2

In CNS, how many compounds serve as neurotransmitters?

Answer 2

21 Compounds Serves as Neurotransmitters

Question 3

It limits the passage of lipid-soluble agents and impedes the entry of drugs into the brain.

Answer 3

Blood Brain Barrier

Question 4

What would happen if we used CNS drugs for a long period of time?

Answer 4

• It decreases side effects
• Increased therapeutic effects
• Tolerance and Physical Dependence

Question 5

What are the dysregulation of the transmitters for the ADHD (attention deficit hyperactivity disorder)?

Answer 5

Serotonin, Norepinephrine, Dopamine

Question 6

What could be the indication for a patient having Narcolepsy?

Answer 6

Unable to move and may collapse such as falling asleep in normal activities

Question 7

It stimulates the release of norephineprine and dopamine from the brain and SNS (Sympathetic Nervous System).

Answer 7

Amphetamines

Question 8

It is being given for a child regulates neurotransmitters and regulate the process inside the brain giving them the longer attention span to do the activities while sitting down (calmly).

Answer 8

Methylprenidate

Question 9

It is being given to treat respiratory depression caused by drug overdose and COPD (chronic obstructive pulmonary disease).

Answer 9

Doxapram

Question 10

Differentiate the Partial Seizures to Generalized Seizures

Answer 10

Partial Seizures = limited spread from the focus to adjacent cortical areas (one hemisphere of the brain)

Generalized Seizures = widely spread throughout both hemispheres of the brain

Question 11

What are the mechanism of anti-epileptic drugs?

Answer 11

1. Suppression of Sodium
2. Suppression of Calcium Influx
3. Antagonism of Glutamate
4. Potentiation of GABA

Question 12

What is the most commonly prescribed anticonvulsant drug?

Answer 12

Phenytoin

Question 13

This drug is included to Benzodiazepine in which this drug is being restricted to acute treatment of status epilepticus and not being recommended for long-term as it has a high potential for addiction.

Answer 13

Diazepam

Question 14

It is one of the direct acting agents in which this drug is most effective for spasticity of cerebral origin such as cerebral palsy, stroke, spinal cord injury.

Answer 14

Dantrolene Sodium

Question 15

Long term spasms caused by anxiety, pain, and trauma are treated in which muscle relaxants?

Answer 15

Centrally Acting Agents

Question 16

With this, there is now a relaxation in skeletal muslces in which there is disrupting on going in the transmission of nerve impulses at the motor end plate.

Answer 16

Neuromuscular Blocking Drugs

Question 17

It is one of the depolarizing blocking drugs that acts like acetycholine but not inactivated by ACHe.

Answer 17

Succinylcholine

Question 18

This drug produces less sedation and less peripheral muscle weakness than dantrolene.

Answer 18

Baclofen

Question 19

It acts as competitive or stabilizing drugs and compete with ACh to prevent muscle from contracting.

Answer 19

Non-depolarizing blocking drugs

Question 20

Using both of these medications cautiously for patients with impaired liver and renal function because these medications are known to be hepatotoxic and neurotoxic. Not being sold over the counter without a prescription.

Answer 20

1. Baclofen and Dantrolene
2. Diazepam