Autonomic Nervous System Drugs

Question 1

What are the two divisions of ANS (Autonomic Nervous System)?

Answer 1

SNS (Sympathetic Nervous System) and PNS (Parasympathetic Nervous System)

Question 2

What is the difference between SNS (Sympathetic Nervous System) and PNS (Parasympathetic Nervous System)?

Answer 2

SNS = carries signals that put your body’s systems on alert (FIGHT OR FLIGHT RESPONSE)
PNS = carries signals that relax those systems (REST AND DIGEST RESPONSE)

Question 3

What is the terminal neurotransmitter of SNS (Sympathetic Nervous System) and PNS (Parasympathetic Nervous System)?

Answer 3

SNS = Norepinephrine
PNS = Acetylcholine

Question 4

4 Receptor Organ Cells for Sympathetic Nervous System (SNS)

Answer 4

Alpha-1
Alpha-2
Beta-1
Beta-2

Question 4

2 Receptor Organ Cells for Parasympathetic Nervous System (PNS)

Answer 4

1. Nicotinic
2. Muscarinic

Question 5

Which system is working to constrict pupils?

Answer 5

Parasympathetic Nervous System (PNS)

Question 6

Which system is working to increase heart rate?

Answer 6

Sympathetic Nervous System (SNS)

Question 7

2 adrenergic agonists based on chemical structure

Answer 7

Catecholamines and Noncatecholamines

Question 8

It stimulates adrenergic receptors

Answer 8

Sympathomimetics/ Adrenergic Agonists

Question 9

In relation to the adrenergic agonists, what is the therapeutic use and receptor of Epinephrine?

Answer 9

Receptor = Alpha-1, Alpha-2, Beta-1, Beta-2

Therapeutic Use = Cardiac Arrest, Asthma

Question 10

In relation to adrenergic agonists, what is the therapeutic use and receptor of Dobutamine?

Answer 10

Receptor = Beta-1

Therapeutic Use = Increases heart rate, shock, force of contraction in heart failure

Question 11

What is the ANTIDOTE for extravasation of norepinephrine and dopamine?

Answer 11

Phentolamine Mesylate (Regitine)

Question 12

It blocks alpha and beta receptor blockers in direct blocking by occupying receptors and indirect blocking by inhibiting release of neurotransmitters.

Answer 12

Adrenergic Blockers

Question 13

It reduces contraction of smooth muscle in bladder and prostate.

Answer 13

Alpha Blockers

Question 14

It decreases heart rate and blood pressure in which might be useful for treating mild to moderate
hypertension, angina pectoris and
myocardial infarction.

Answer 14

Beta Blockers

Question 15

In relation to adrenergic antagonist, what is the therapeutic use and receptor of Pindolol?

Answer 15

Receptor = Beta-1, Beta-2

Therapeutic Use = Decrease CO (cardiac output), HR (heart rate) for patients with heart block

Question 16

In relation to adrenergic antagonist, what is the therapeutic use and receptor of Terazosin?

Answer 16

Receptor = Alpha-1

Therapeutic Use = Hypertension

Question 17

What specific vital signs should be check in prior to giving adrenergic antagonist?

Answer 17

Heart Rate or Apical Pulse or Radial Pulse

Question 18

Enymes that breaks Acetylcholine

Answer 18

Acetylcholinesterase

Question 19

Therapeutic use of Carbachol

Answer 19

Used locally to constrict pupils and decrease IOP (Intraocular pressure)