Central Nervous System drugs Flashcards
Conducting an action potential down to axon of the neuron.
Axonal Conduction
A process by which information is carried across the gap between neuron and postsynaptic cell.
Synaptic Transmission
CNS contains __ compounds that serves as neurotransmitters.
21
Dopamine, Epinephrine and Serotonin is what group of CNS drugs
Monoamine
It impedes the entry of the drugs into the brain where children are much more sensitive to CNS drugs than adults.
Blood Brain Barrier
ADHD stands for:
Attention Deficit Hyperactivity Disorder
CNS stimulant that stimulates the release of NE and DA from the brain and SNS.
Amphetamine
Treatment of narcolepsy
Modafinil
Treatment of respiratory depression caused by drug overdose and COPD
Doxapram
Slowly progressive neurodegenerative disorder characterized by tremor, rigidity, postural instability and slowed movement.
Parkinson’s Disease
Excitation undergoes limited spread from the focus to adjacent cortical areas.
Partial Seizures
Defined as involuntary contraction of a muscle or muscle group and often painful and decrease level of functioning.
Muscle Spasm
It decrease response occuring in the coarse of prolonged drug use.
Tolerance
A state in which abruptly discontinuation of drug use will precipitate a withdrawal syndrome.
Physical Dependence
Drugs that directly/indirectly caused activation of dopamine receptors.
Dopaminergic drugs
It is a goal that improves the patient’s ability to carry out activities of daily life and also improves body kinesia, gait disturbance and postural instability.
Therapeutic Goal
________ acting agents use for treatment of acute muscle spasms caused by anxiety, pain and trauma. Treat spasticity from condition as MS and cerebral palsy.
Centrally Acting Agents
Abstinence maintenance that decrease unpleasant effects resulting from abstinence (anxiety/restlessness).
Acamprosate
Abstinence maintenance to opioid antagonist that suppresses craving and unpleasant effects of alcohol.
Naltrexone
This is an abstinence maintenance that take PO, daily, and oversion therapy that should not be used concurrently with alcohol.
Disulfiram
