Central Nervous System Drugs

Question 1

___ refers to the study of drugs that alter processes controlled by the Nervous System

Answer 1

Neuropharmacology

Question 2

Ways on how neurons regulate other cells

Answer 2

1. Axonal Conduction
   - conducting an action potential down the axon of the neuron
2. Synaptic Transmission
   - process by which information is carried across the gap between neuron and postsynaptic cell

Question 3

This drug is used for psychiatric disorders, suppression of seizures, relief if pain, production of anesthesia

Answer 3

Central Nervous System (CNS) Drugs

Question 4

It is found in the CNS, and has a special protection called ___

Answer 4

Blood Brain Barrier

Question 5

It is a slowly progressive neurodegenerative disorder characterized by tremor, rigidity, postural instability, and slowed movement

Answer 5

Parkinson’s Disease

Question 6

___is effective against partial seizures and generalized tonic-clonic seizures but not absence seizures (Barbiturates)

Answer 6

Phenobarbital

Question 7

It is most commonly prescribed anticonvulsant drug (Hydantoins)

Answer 7

Phenytoin

Question 8

CNS Stimulants: Amphetamines

Answer 8

1. Methylphenidate
2. Modafinil
3. Analeptics: Xanthine
4. Doxapram

Question 9

This type of drug deployed directly/ indirectly that causes activation of dopamine receptors is called ___

Answer 9

Dopaminergic Drugs

Question 10

This type of drug deployed that blocks receptors for ACh (acetylcholine) is called ___

Answer 10

Anticholinergic Agents

Question 11

It is a group of disorders characterized by excessive excitability of neurons in the CNS

Answer 11

Epilepsy

Question 12

It is a general term that applies to all types of epileptic events

Answer 12

Seizures

Question 13

It is an abnormal motor phenomenon

Answer 13

Convulsion

Question 14

___ is a treatment for absence, atypical absence seizures

Answer 14

Clonazepam

Question 15

Adverse effects of Benzodiazepine

Answer 15

• drowsiness
• confusion
• ataxia
• weakness
• dizziness
• nystagmus
• vertigo
• headache
• tremor
• glassy eyed apperance

Question 16

3 Carboxylic Acid Derivatives

Answer 16

1. Valproate
2. Valproic Acid
3. Divalproex

Question 17

___ binds to a carrier protein and act at a receptor resulting in increased GABA in the brain

Answer 17

Gabapentin

Question 18

It defines as involuntary contraction of a muscle or muscle group

Answer 18

Muscle Spasm

Question 19

It mimics inhibitory actions of GABA in the CNs and produces less sedation and less peripheral muscle weakness than dantrolene

Answer 19

Baclofen

Question 20

___ is treated with baclofen, diazepam, and dantrolene

Answer 20

Spasticity