Central Nervous System

Question 1

Antipsychotic Agents (2 typical, 4 atypical)

Answer 1

Typical Antipsychotics - Haloperidol and Chlorpromazine

Atypical Antipsychotics - olanzapine, risperidone, quetiapine, clozapine

Question 2

Additional anti-mania drugs (2 possible)

Answer 2

Valproic Acid and Lithium Carbonate

Question 3

Anti-Depressant Drugs (6 possible)

Answer 3

Imipramine, lofepramine, citalopram, fluoxetine, sertraline, venlafaxine

Question 4

Anti-obesity drugs (1)

Answer 4

Orlistat

Question 5

Drugs for nausea and vomiting (5 possible)

Answer 5

H1 Antagonist - Cyclizine
Dopamine D2 Antagonists - Metclopramide, Domperidone
5-HT (Serotonin) Antagonist - Ondansetron
Anti-Muscarinic - Hyoscine

Question 6

Analgesics (6 possible)

Answer 6

Aspirin, Paracetamol, Morphine, Diamorphine (Heroin), Codeine, Tramadol

Question 7

Anti-Epileptic Drugs (4 possible)

Answer 7

Carbamazepine, Lamotrigine, Phenytoin, Sodium Valproate

Question 8

Drugs used in Parkinson’s Disease (8 possible)

Answer 8

Dopamine Receptor Agonists - Apomorphine, Bromocriptine and Ropinirole
L-dopa supplements - Levodopa
MAO type B inhibitors - Selegiline
COMT inhibitors - Entacapone
Antimuscarinics - Amantidine and Procyclidine

Question 9

Drugs used for Dementia (3 possible)

Answer 9

Donepezil (palliative treatment - improves cognition and behaviour of people with Alzheimer’s but does NOT slow progression of Alzheimer’s disease - it is a centrally acting reversible acetylcholinesterase inhibitor).
Galantamine (treatment of mild to moderate Alzheimer’s Disease and memory impairments particularly of vascular origin. It is a synthetic alkaloid with acetylcholinesterase inhibiting properties).
Memantine (blocks NMDA receptors - modest effect in moderate to severe Alzheimer’s and dementia with Lewy bodies).

Question 10

Anxiolytics (drugs used in treatment of anxiety disorders) (2 possible)

Answer 10

Diazepam, lorazepam