Central Dogma Flashcards

0
Q

DNA

A

Deoxyribonucleic acid
Double helix
Polymer of nucleotides (nucleotides are covalently linked together in a single strand)
A,T,G,C

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1
Q

Gene

A

Unit of genetic information that provides instructions for a specific property of an organism

Provides the instructions to make a protein

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2
Q

Central Dogma

A

DNA -> RNA -> Protein
Transcription Translation

Place where we can treat disease (antibiotics)

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3
Q

Transcription factors

A

Proteins at bind to the regulatory sequence. Of DNA to control gene expression

Gene expression can be positively or negatively regulated
Negative: when the binding of a repressor protein inhibits inscription
Positive: when the binding of an activator protein stimulates transcription

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4
Q

Regulatory region

A

Turn on/off gene

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5
Q

Cell specific regulation and combination control

A

Differential expression of genes located in different cells varies because of differing amounts and identities of activators present

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6
Q

Transcription

A

Process of synthesizing mRNA from a gene

3 steps:

  1. Initiation
  2. Elongation
  3. Termination
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7
Q

3 steps of transcription

A
  1. Initiation
  2. Elongation
  3. Termination
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8
Q

mRNA

A

Carries information from the gene to the site of protein synthesis

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9
Q

RNA v DNA

A

RNA DNA
single stranded Double helix
U T
Ribose Deoxyribose

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10
Q

Goal of translation

A

Read the sequence of one biological polymer to synthesize another->generate a polypeptide chain

How?
Tools
Code

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11
Q

Ribosome

A
Tool of translation
The molecule that binds to mRNA, decodes it, and covalently links amino acids together 
Complex of protein and RNA
2 subunits 30s and 50s
Acts as an enzyme
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12
Q

tRNA

A

Tool of translation

Acts as an adapter allowing the ribosome to decode mRNA into a polypeptide chain

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13
Q

Codon

A

Set of 3 nucleotides read together that code for a specific amino acid

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14
Q

Translation

A

The process of reading the mRNA and synthesizing the corresponding polypeptide chain

3 key steps:

  1. Initiation
  2. Elongation
  3. Termination
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15
Q

Peptide bond

A

A specific covalent linkage between two amino acids

16
Q

Polypeptide

A

Many amino acids linked together

A polymer of amino acids

17
Q

Protein

A

Polymer of amino acids