Central Dogma Flashcards
RNA Polymerase I
Makes most rRNA genes
RNA Polymerase II
reads DNA sequence to make mRNA
RNA polymerase III
makes tRNA
Where is Bre Found
-35 from start
transcription factor TFIIB
Where is TATA found
-30 from start
transcription factor TBP
Where is INR
right at transcription point (initiator)
Tanscription factor TFIID
Where DPE found
+30 from transcription point
Transcritpiton factor TFIID
Amino Acid is attached to ____ end of tRNA
3’
First Amino acid binds to what site on rRNA?
Met binds to P site of rRNA which then allows the large rRNA subunit to come in
5’ Capping and addition of the poly A tail occurs on the
the pre-mRNA as it is forming the mautre mRNA in the nucleus
Introns are normally flanked by which bp’s
5’ - Exon - (GU-Intron- AG)- Exon-3’
Introns are removed by?
snRNPs: small nuclear ribonucleoprotein particles
HAT
histone acetylating protein: unwinds DNA and allows for easier transcription
HAT binds to activator to unwind
HDAC
Histone Deacetylase: removes acetyl group from histone making it bind DNA tighter
HDAC binds to repressor to tightly coil DNA