Cellulitis Flashcards
1
Q
What is cellulitis
A
An infection of the deep dermis and subcutaneous tissue presenting with expanding erythema , warmth , tenderness and swelling.
2
Q
What two bacteria is likely to cause cellulitis?
A
Staphylococcus aures and streptococcus pyogenes
A gram positive bacteria
3
Q
Which antibiotic would you use to treat cellulitis? And why
A
Flucolaxacillin - 500mg QDS (4 times a day) and for 7 days.
This is effective against both staph aures and strep pyogenes.
4
Q
What class of antimicrobial is flucloxacillin?
A
Beta lactam
5
Q
What mechanism of action is flucloxacillin?
A
Cell wall synthesis inhibition
6
Q
Examples of virulence factors of staphylococcus aures
A
- Secreted coagulate which is an enzyme that causes citrates plasma to clot. This restricts access by neutrophils.
- Some bacteria that have a capsule.
- Cell wall contains protein A which binds to Fc region of IgG - exerting an anti opsonins
