cellular responses to stress and toxic insults 2 Flashcards
sequential development of biochemical and morphologic changes
what are some signs of reversible injury?
swelling
blebbing
detached ribosomes
clumping of nuclear chromatin
regarding necrotic cells…
what are signs of karyolysis?
fading of basophilia f the chromatin
change that reflects loss of DNA because of enzymatic degradation by endonucleases
regarding necrosis of cells…
what are signs of pyknosis?
nuclear shrinkage
increased basophilia
chromatin condenses into solid, shrunken basophilic mass
regarding necrosis of cells…
what are signs of karyorrhexis?
pyknotic nucleus undergoes fragmentation
nucleus in the necrotic cell totally disappears
where is coagulative necrosis usually seen?
heart
coagulative necrosis
where is caseus necrosis most common?
lungs
TB
caspases and cytochrome C activate…?
apoptosis