cellular function Flashcards
a. Outline basic principles of structure and function of membranes
Function- form a barrier around cell and cell compartments, control chemical environment, recognition and communication
structure made of a phospholipid bilayer - head polar and hydrophilic and tail is hydrophobic = amphipathic
spontaneously form I layer with tails facing in
name the cell compartments
cytosol (gray), endoplasmic reticulum, Golgi apparatus, nucleus, mitochondrion, endosome, lysosome, and peroxisome
function of nucleus
Stores hereditary material and coordinates growth, metabolism and protein synthesis
function of mitochondria
Generating + transforming the energy –vital in metabolisms like oxidative phosphorylation
function of Endoplasmic reticulum
Storage + secretion of proteins and lipid
function of Golgi
Modifies proteins and packages them into vesicles
function of Golgi
Modifies proteins and packages them into vesicles
function of endoscopes and lysosomes
Stores digestive enzymes Transports materials from the Golgi to the lysosome
Describe behaviour of cell compartments and their interrelationships: secretion and intake
Some proteins are made on ribosomes that are free in the cytoplasm.
▪ From there some proteins move into the nucleus while others are directed into
mitochondria. Proteins destined to RER have a signal peptide telling them where to go
▪ Signal peptide binds to ER. Rest of protein is translated. Membrane proteins and proteins to be secreted are produced by ribosomes on the endoplasmic reticulum (ER). This organelle produces, processes, and ships out both proteins and lipids.
c. roles of the cytoskeleton: microtubules, Myosin and Actin, microtubule associated proteins
-The actin cytoskeleton provides thrusting and contractile forces,
- microtubules form a
polarized network allowing organelle and protein movement throughout the cell. - Intermediate filaments are
generally the most rigid component = maintenance of the overall cell shape.
smooth vs rough ER function
SMOOTH ER – small, interconnected tubules. It functions in the biosynthesis of lipids, phospholipids, and cholesterol for steroid (in the liver - cytochrome P450 for detox of drugs and alcohol; in muscle the SER is termed the sarcoplasmic reticulum and stores and releases Ca2+ ion for muscle contraction).
ROUGH ER - broad flat cisternae studded with ribosomes - major role in protein synthesis.
The two types interconnect and both are connected to the nuclear envelope
elationship between
endosomes, lysosomes and Golgi and their functions
Endosomes receive materials taken into the cell through endocytosis into vesicles. The endosomes sort and recycle membrane components to the cell surface and send the rest on to the lysosomal system, where they are joined by Golgi vesicles containing enzymes that break down the vesicle contents into fundamental component that can be reused by the cell.
Phagocytosis is similar but a number of things can occur after/during. The cell could present some part of the material on its cell surface- antigen presentation.