Cells & Synapses Flashcards
Neurons
“MVP, teachers pet, valedictorian”
Early anatomists viewed neurons as continuous series of tubes
Neuron doctrine
Ramon y Cajal (1852-1934)
Cells of the brain (neurons and otherwise) are separate and independent in structure and function.
Informations is transmitted across tiny gaps (synapses)
Axons _______, dendrites _______.
Speak, listen
4 zones of neuron anatomy
Input (dendrites)
Integration (cell body)
Conduction (axon)
Output (axon terminals)
Types of neurons and their functions
Sensory neurons- perceive senses, diverse shapes depending on associated sense, etc. LONG.
Interneurons- send electrical signals from one neuron to the next. SHORT.
Motoneurons- motor neurons, cause muscular contractions. LONG.
Glial Cells/”Glia”
Types
“Runner-up, unsung hero, best sportsmanship”
Astrocytes
Oligodendrocytes
Microglia
(some glia respond to brain injury by swelling. This edema damages neurons and is responsible for many symptoms of brain injuries)
Astrocytes
coordinate neuronal function
provide structure (scaffolding for neuron growth)
provide nutrients from blood
protection (blood brain barrier, preserve basic health of neurons)
diverse function
Oligodendrocytes
(Called Schwann cells when in PNS)
Form myelin (the fatty sheath on axons that insulates axons and increases speed and efficiency)
More specialized function
Microglia
Digest dead or damaged cells
Remove debris “clean up crew”
More diverse function
Synapse
Tiny gap that information is transmitted across
Estimated 10^15 synapses in the brain
Axon Hillock
On the cell body, converts input into electrical signals
Axon
Conducts electrical signals to innervate target
Acts as connection of cell body and dendrites
Types of axonal transport
Anterograde- forward, away from cell body, moves proteins to axon terminals
Retrograde- backward, toward cell body from axon terminal, move debris for recycling
Axodendritic (axon to dendrite)
Axoaxonic (axon to axon)
Axosomatic (axon to cell body/soma)
Action Potential
Electrical nerve impulse
Short lived change in the cells membrane voltage
Cell to cell communication
“Spikes” or a neuron fires (frequency of neuron firing)
Neuroplasticity
Capacity for continual remodeling of connections between neurons