Cells and tissues

Question 1

Epidermolysis bullosa

Answer 1

Arises from epithelial dysfunction

Inherited blistering skin disorder

Question 2

Cystic fibrosis

Answer 2

Arises from epithelial dysfunction
Mutation in CFTR gene
Defective chloride channel on apical surface of epithelial cells
Less water in mucous so it thickens. This builds up and cannot be expelled

Question 3

Marfan syndrome

Answer 3

A genetic disorder of defective connective tissue

Usually causes people to be tall and thin, with long arms, legs, fingers and toes