Cell Wall Inhibitors besides Cephalosporins and Penicillins and Protein Synth Inhibitors

Question 1

Aztreonam mech

Answer 1

Prevents peptidoglycan cross linking by binding to PBP3. Synergistic with aminoglycosides

Question 2

Aztrenoam mech

Answer 2

Gram negative rods only

Question 3

Works by binding D-Ala D-Ala cross links

Answer 3

Vancomycin

Question 4

Binds to Protein Binding Protein

Answer 4

carbapenems

Question 5

MRSA drug

Answer 5

Vancomycin

Question 6

VANCOMYCIN toxicity besides redman syndrome

Answer 6

NOT
Nepphrotoxic
Ototoxic
Thrombophlebitis

Question 7

How do you prevent red man syndrome in pts receiving vancomycin

Answer 7

Pre-medicate with antihistamines

Question 8

Protein synthesis inhibitors work well on which typeof bacteria

Answer 8

gram negatives

Question 9

Buy AT 30, CCEL at 50. What does this mean

Answer 9

Mnemonic for where the protein synthesis inhibitors work

AT 30= Aminoglycosides and Tetracyclines work at the 30s subunit

CCEL at 50= Chloramphenicol, Clindamycin, Erythromycin, Linezolid work at 50s subunit