cell transport and krebs cycle Flashcards
cholesterol molecules in cell membrane
give rigidity
at regular intervals
proteins in the membrane
integral - go the entire way thru (channel protein)
peripheral - located inside or outside
lipid bilayer impermeable to
most charged/ polar substances
non lipid soluble
permeability factors
solubility in lipids
molecule size
driving force - up/down gradient
passive transport
down gradient
thru lipid bilayer - lipid soluble
thru ion channel - water soluble
using a carrier - water soluble
lipid soluble
lipids, small alcohols, respiratory gas, urea
conc grad driven
across lipid bilayer
need integral membrane proteins
- water, small ions, sugars and amino acids (facilitated diffusion)
facilitated diffusion
solute binds to specific transport membrane and is released on other side
glucose out of cell
fructose in cell
depends conc grad an no of transport membrane
gated channel protein
specific to ion
selective and specific
open or closed
(neuron)
primary vs secondary active transport ***
primary - energy derived directly from atp (metabolic/ atp hydrolysis)
secondary - derived indirectly from atp (transport with Na+ or H+) tag along. glucose and amino acids
antiporters and symporters*
pinocytosis
engulfing small particles and fluids
phagocytosis
engulfing large particles
receptor mediated endocytosis
into the cell involving the caveolae regions
osmosis definition
movement of water from a low solute conc to a high solute conc across a semi permeable membrane (uses aquaporin)
osmosis driving forces
osmotic pressure = solute conc
water follows salt
tonicity
measure of a solution ability to change volume of cells by altering their water content
hypotonic - cells swell
hypertonic - cells shrink
catabolism
anabolism
cata breaks down
and build up
atp structure
3 phosphate groups
adenine base
5C sugar / ribose
used for muscle contraction, active transport, movement of structure in cell, nerve conduction
energy generation stages
1 everything broken down to monomers
2 monomers degraded to simple key compounds
3 citric acid/ krebs cycle & oxidative phosphorylation
carbohydrate metabolism
primarily glucose metabolism
1 glycolysis 2 krebs cycle 3 electron transport chain & oxidative phosphorylation
1 glucose + 6O2 –> 6water + 6 co2 + 36 ATP + heat
cellular respiration types
anaerobic - no oxygen - glycolysis
aerobic - oxygen - oxidative phosphorylation
cellular respiration process
glycolysis
formation acetyle CoA (mito)
krebs cycle (mito) (aero)
electron transport chain (mito) (aero)
glycolysis **
glucose + 2NAD+ +2ADP +2inorganic phosphate –> 2 pyruvic acid + 2NADH2 +2ATP
activate glucose (use 2 atp) create 4 ATP
glycolysis steps
1 activate glucose
2 sugar cleavage - 6C sugar split into 2 3C. each has phosphate group
3 oxidation & ATP formation - phosphates split from sugar bond w ADP to form ATP. remaining 3 c are pyruvic acid
if oxygen pyruvic acid to krebs cycle, if not turn into lactic acid