Cell Transport Flashcards
Endocytosis
Exocytosis
bulk transport of materials into the cell
balk transport of material outside the cell
Metabolism of proteins fats carbs nucleic acids
breaking down and rebuilding nutrients
proteins => aa => proteins
fats => fatty acids => fats
carbs => glucose => carbs
nucleic acids => nucleotides => nucleic acids
animal form => intermediary subunits => human form
(=>1 = catabolism) (=>2 = anabolism)
Catabolism
“cut up”
breaking down nutrients
Anabolism
“Apex”
building up
Uses ATP
Enzymes
lower activation energy.
don’t change deltaG
Competitive inhibitor Enzyme
must be similar shape to substrate
binds to active site, stops substrate from being able to bind and thus stops activity
the concentration of substrate affects its effectiveness
Non-competitive Inhibitor Enzyme
form of allosteric interaction
blocks reaction by interacting with enzyme at different point.
substrate still able to enter active site but reaction cannot occur.
substrate concentration has no affect on effectiveness.
Uncompetitive
form of allosteric interaction
2 substrates w same enzyme in 2 different active sites of same enzyme
1 active site affects the others ability to work
ie. enzyme can only do one job, whichever substrate gets to it first is the one it catalyses
substrate concentration affects effectiveness
allosteric inhibior
second location on enzyme that affects active site
Osmoregulation
hypertonic (shrivelled / plasmolysed)
isotomic (normal / flaccid)
Hypotonic (lysed or burst / turgid)
animal / plant
Active transport
uses ATP, against concentration gradient sodium/pottasium pump - create conc. graident to passivley diffuse large glucose into cell - 33% of cell energy Na+ out of cell K+ into cell
Passive transport
No atp used
diffusion - random movement of molecules net high=>low
osmosis - h20 diffusion through semi permeable membrane
- equal free h20 molecules on each side = concentration
proteins used
- channel proteins - tunnel, a constant flow of molecules
- carrier proteins - fixed-rate, open, 1 molecule in, close, out, repeat
- aquaporins - channel proteins allow water across
- most lipids block polar molecules such as H20
Cell Communication
Local
Long-distance
Local - direct contact or cell-cell communication
long-distance - signal transduction pathways
- reception, transduction, response
1. reception
- signal molecule (ligand) and receptor (plasma membrane protein) bind
- causes receptor shape change - very specific
2. transduction
- each step signal changes form/shape
- phosphorylation cascades (sometimes - all but G protein)
- each stage adds phosphate to next step to activate it
3. response
- regulated in many steps
- signal amplifies with each protein in phosphorylation pathway
- scaffolding proteins increase signal efficiency
Apoptosis
Programmed cell death in orderly fashion
Necrosis
Unplanned cell death through external factor ie. trauma (burn, cut…)