Cell Surface Proteins Flashcards
TCR
T cells
Binds antigen-MHC complex
CD3
T cells
Associated with TCR for signal transduction
CD28
T cells
Binds B7 on Antigen-Presenting Cells
CD4
Helper T cells
CD40 ligand
Helper T cells
CD8
Cytotoxic T cells
Ig
B cells
Binds antigen
CD19
B cells
CD20
B cells
CD21
B cells
Receptor for Epstein-Barr Virus
CD40
B cells
Macrophages
MHC II
B cells
Macrophages
B7
B cells
Macrophages
CD14
Macrophages
Fc receptor
Macrophages
Enhances phagocytosis
C3b receptor
Macrophages
Enhances phagocytosis
CD16
NK cells
Binds Fc of IgG
CD56
NK cells
Unique marker for NK cells
CD1a
Langerhans cells
Histeocytosis
CD2
Adhesion molecule for T-cells, NK cells, and LAK cells
CD10
Marker for ALL
CD 15 & 30
Hodgkin’s lymphoma
CD45
Leukocytes marker
Useful in surgical patho to differentiate leukocyte from epithelial malignancy
Co-expression of CD5 and CD19
Cancer
CD1a
Langerhans cells
Histeocytosis
CD2
Adhesion molecule for T-cells, NK cells, and LAK cells
CD10
Marker for ALL
CD 15 & 30
Hodgkin’s lymphoma
CD45
Leukocytes marker
Useful in surgical patho to differentiate leukocyte from epithelial malignancy
Co-expression of CD5 and CD19
Cancer
CD1a
Langerhans cells
Histeocytosis
CD2
Adhesion molecule for T-cells, NK cells, and LAK cells
CD10
Marker for ALL
CD 15 & 30
Hodgkin’s lymphoma
CD45
Leukocytes marker
Useful in surgical patho to differentiate leukocyte from epithelial malignancy
Co-expression of CD5 and CD19
Cancer
CD1a
Langerhans cells
Histeocytosis
CD2
Adhesion molecule for T-cells, NK cells, and LAK cells
CD10
Marker for ALL
CD 15 & 30
Hodgkin’s lymphoma
CD45
Leukocytes marker
Useful in surgical patho to differentiate leukocyte from epithelial malignancy
Co-expression of CD5 and CD19
Cancer