Autoantibodies and Associated Disorders Flashcards

1
Q

Anti-Acetylcholine Receptor

A

Myasthenia Gravis

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2
Q

Anti-basement membrane

A

Goodpasture Syndrome

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3
Q

Anti-cardiolipin

A

Systemic Lupus Erythematosus
Anti-Phospholipid Syndrome

(Also called lupus anticoagulant)

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4
Q

Anti-centromere

A

Limited Scleroderma

CREST syndrome

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5
Q

Anti-desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA

A

Systemic Lupus Erythematosus

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7
Q

Anti-Smith

A

Systemic Lupus Erythematosus

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8
Q

Anti-glutamate decarboxylase

A

Type 1 Diabetes Mellitus

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9
Q

Anti-hemidesmosome

A

Bullous Pemphigoid

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10
Q

Anti-histone

A

Drug-Induced Lupus

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11
Q

Anti-Jo-1

A

Polymyositis

Dermatomyositis

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12
Q

Anti-SRP

A

Polymyositis

Dermatomyositis

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13
Q

Anti-Mi-2

A

Polymyositis

Dermatomyositis

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14
Q

Anti-microsomal

A

Hashimoto Thyroiditis

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15
Q

Anti-thyroglobulin

A

Hashimoto Thyroiditis

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16
Q

Anti-mitochondrial (AMA)

A

Primary Biliary Cirrhosis

17
Q

Anti-nuclear Antibodies (ANA)

A

Systemic Lupus Erythematosus

Non-specific (autoimmune hepatitis as well)

18
Q

Anti-Scl-70 (Anti-DNA Topoisomerase I)

A

Scleroderma (diffuse)

19
Q

Anti-smooth muscle (ASMA)

A

Autoimmune hepatitis

20
Q

Anti-SSA (anti-Ro)

A

Sjögren Syndrome

21
Q

Anti-SSB (Anti-La)

A

Sjögren Syndrome

22
Q

Anti-TSH receptor

A

Graves Disease

23
Q

Anti-U1 RNP (Ribonucleoprotein)

A

Mixed Connective Tissue Disease

24
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangitis (Wegener)

25
Q

IgA anti-endomysial

A

Celiac disease

26
Q

IgA anti-tissue transglutaminase

A

Celiac disease

27
Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangitis

Churg-Strauss syndrome

28
Q

Rheumatoid Factor

antibody, most commonly IgM, specific to IgG Fc region

A

Rheumatoid arthritis

29
Q

Anti-CCP

A

Rheumatoid arthritis