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Immunology > Cell Surface Markers > Flashcards

Cell Surface Markers Flashcards

1
Q

Which cell is associated with CD2 marker?

A

Pro T cells - mature T cells

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2
Q

Which cell is associated with the CD3 marker

A

T cells and thymocytes

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3
Q

What is the function of the CD3 marker

A

Associated with the TCR; transmits the signal into the cell

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4
Q

Which cell is associated with CD4 marker

A

Th cells and thymocytes; 2/3 of peripheral T cells

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5
Q

What is the function of the CD4 marker

A

Co-receptor for class II MHC, receptor for HIV-1 and HIV-2 gp120

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6
Q

Which cell is associated with CD8 marker?

A

Tc cells and thymocytes

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7
Q

What is the function for the CD8 marker?

A

Co-receptor for class I MHC

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8
Q

Which cell is associated with CD14 marker?

A

Myelomonocytic cells

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9
Q

What is the function of the CD14 marker?

A

receptor for LPS and LPS binding protein complex

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10
Q

Which cell is associated with the CD11 marker?

A

Lymophocytes, granulocytes, monocytes, and macrophages

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11
Q

What is the fucntion of the CD11 marker

A

An alpha integrin associated with CD18 to form different receptors

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12
Q

Which cell is associated with the CD16 marker

A

Neutrophils, NK cells, macrophages

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13
Q

What is the function of the CD16 maker

A

component of the IgG Fc receptor that facilitates ADCC and phagocytosis

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14
Q

Which cell is associated with the CD18 marker?

A

Leukocytes

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15
Q

What is the function of the CD18 marker

A

Component of an adhesion molecule required for cellular recruitment and many cell-to-cell interactions
Deficiency in neutrophil function/LAD

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16
Q

Which cells are associated with the CD19/CD20 markers?

A

B cells

17
Q

Which cell is associated with CD25 marker

A

Activated T cells

18
Q

What is the function of the CD25 marker

A

High affinity IL-2 receptor, promoting T cell proliferation

19
Q

Which cell is associated with CD34

A

Pluripotential stem cells

20
Q

Which cells are associated with the CD40 marker

A

B cells and other APCs

21
Q

What is the function of the CD40 marker

A

Transmit a signal from the Th cell to the bell cell to promote proliferation, isotype switching and memory

22
Q

Which cell is associated with the CD56 marker

A

NK cell marker

Immunology (4 decks)

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