Cell structure, Chapter 4 Flashcards

1
Q
  • Cells were first observed in the 17th century by?
A

Robert hooke

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2
Q

Modern cell theory is based on 3 principles

A
  • All organisms composed of one or more cells
  • Cells are smallest living things
  • Cells arise only by division of a previously existing cell
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3
Q

Solutes move from a high concentration to low concentration

A

Diffusion

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4
Q

Rate of diffusion is affected by

A
  • surface area available for diffusion
  • temperature
  • concentration gradient of diffusing substance
  • distance over which diffusion must occur
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5
Q

Surface Area to volume ratio

A

As a cell’s size increases, its volume increases much more rapidly than its surface area
- small cells have an advantage over an larger cells

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6
Q

Light microscopes

A
  • Use magnifying lenses with visible light
  • Can view some cells, but few cellular structures
  • Limit to resolution using light
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7
Q

Electron microscopes

A
  • Use a beam of electrons
  • Able to view cellular structures
  • Transmission electrons microscopes through the material
  • Scanning electron microscopes beam electrons onto the specimen surface
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8
Q

Cells share simple structural features

A
  • A localized area where genetic material is stored
  • The cytoplasm
  • All cells have ribosomes
  • A plasma membrane
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9
Q

Prokaryotic

A
  • Bacteria and Archaea
  • Simple cellular structure- an organization
  • Lack of a membrane-bound nucleus
  • Do not have an internal membrane system
  • Huge diversity in prokaryotic metabolism, function and ecology
  • Cytoplasm surrounded by a plasma membrane and encased by a cell wall
  • Contain ribosomes for protein synthesis
  • No membrane-bound organelles- operate as a single unit
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10
Q

Bacteria cell walls

A
  • Composed of Peptidoglycan, a carbohydrate matrix cross-linked with shirts polypeptide units
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11
Q

some antibiotics function by disrupting the peptidoglycan layer of bacteria cells

A

killing the cells

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12
Q

Cell walls

A

Protect the cell, maintain shape and prevents excess water loss/uptake

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13
Q

long threadlike structures protruding from the surface of a cell, used in locomotion

A

Flagella

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14
Q

Eukaryotic cells

A
  • Cells are broken up into compartments through the endomembrane system and organelles allowing the simultaneous and independent biochemical processes to occur
  • The nucleus acts as the information center
  • Largest organelle
  • The nucleus contains genetic information
  • Contain a single nucleus
  • Nuclear envelope; bounded by 2 phospholipid bilayer membranes
  • Nuclear pores; occur across the nuclear envelop- allowing ions and small molecules to diffuse freely- transport proteins that function in the nucleus
  • Nuclear envelop covered with fibers that make up the nuclear lamina
  • Gives the nucleus its shape and is involved in cell division
  • DNA is divided into chromosomes organized into a complex structure called chromatin
  • The structure of chromatin affects the function of DNA
  • Nucleolus; area of concentrated RNA synthesis and ribosome assembly within the nucleus
  • To make proteins cells must first make ribosomes
  • Ribosomes: complex structures and are made up of 2 subunits
  • Messenger RNA(mRNA): coding information from DNA and is used to direct synthesis
  • Ribosomes are either free or membrane-associated
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15
Q
  • The interior of the cell is packed with internal membranes
  • divide cells into compartments
A

Endomembrane system

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16
Q
  • largest internal membrane
  • phospholipid bilayer embedded with proteins
  • divided into 2 subdivisions
A

Endoplasmic reticulum (ER)

17
Q
  • proteins synthesized on the surface of the RER are destined to be exported from the cell, sent to lysosomes or vacuoles, or embedded in the plasma membrane
  • Protein leaves the RER to be sorted to their final destination
A

The rough ER (RER) is a site of protein synthesis

18
Q
  • Membranes of the SER contain many embedded enzymes, involved in the synthesis of carbohydrates and lipids
  • The majority of membrane lipids are assembled in the SER
  • SER stores intracellular Ca2+, used in diverse signaling pathways
  • The SER modifies foreign substances to make them less toxic
  • in the liver enzymes in the SER carry out detoxification
A

The Smooth ER (SER) has multiple roles

19
Q

The ratio of RER to SER in cells depend on

A

The cells function

20
Q
  • Sorts and packages proteins
  • complex flattened stacks of membranes
  • size and # of cistern varies across organism and cell types
  • Abundant in cells that manufacture and secrete proteins
A

Golgi apparatus

21
Q
  • located near ER
  • ## proteins arrive in transport vesicle that bud off ER
A

Cis face

22
Q
  • proteins exit and are discharged in secretory vesicles
A

Trans face

23
Q

Add short sugar chains
- Glycoproteins or glycolipids

A

Glycosylation

24
Q
  • digestive vesicles that arise from the GA
  • contain many enzymes to degrade macromolecules
  • break down old organelles and recycle their molecules
  • have optimal activity at an acid pH
  • conditions could kill cell=keep compartmentalized
  • activated by fusing with what they will breakdown
  • fission activates proton pumps
  • pump H+ in and lowers pH- activating digestive enzymes
A

Lysosomes

25
Q

Tay-Sachs disease

A
  • caused by the loss of function of a single lysosomal enzyme
  • necessary to breakdown membranes glycolipid found in nerve cells
  • leads to seizures and muscle rigidity
26
Q

Organelles consisting of a neutral lipid core, surrounded by a single layer of phospholipid

A

lipid droplets