Cell Proliferation + death

Question 1

Neoplasia
Tumour
Mutagenesis
Oncogenesis

Answer 1

Neoplasia = abnormal proliferation of cells
Tumour = swelling due to abnormal growth of tissue
Mutagensis = production of genetic mutations
Oncogenesis = development of a tumour

Question 2

Types of neoplasia + histology

Answer 2

Carcinomas - epithelial - disordered sheets or nests
Sarcomas - connective tissue - haphazard spindle-like cells
Lymphomas - lymphoid - diffuse pattern
Leukemia - blood producing cells - abnormal cells in bone marrow
Neuroblastomas - SNS - small, round cells in nests

Question 3

Necrosis definition and function

Answer 3

= accidental cell death
Pathological
Cell swelling
lysosomal cells leak
causes: injury, infection, cancer etc.
causes an immune response

Question 4

Apoptosis

Answer 4

= programmed cell death
physiological + regulated
cell shrinking
deletion of infected or transformed cells etc
apoptotic bodies formed