Cell Membrane and Transport Flashcards
Roles of the plasma membrane
Controls exit/entry for substances
Isolates organelles / enzymes (can transport enzymes)
Internal transport system
Provides surface for biochemical reactions
Allows cell to change shape
Function of phospholipids in the membrane
Allow lipid soluble substances to enter/leave
Prevent water soluble substances from entering/leaving
Makes membrane flexible
Role of cholesterol in membrane
Provides strength
Hydrophobic- prevents water and ion loss from cell
Binds to lipid tail to restrict movement (doesn’t make them fully rigid)
Makes membrane rigid at higher temps
Types of proteins in the membrane
Extrinsic- don’t span the bilayer (provide mechanical support and cell receptors)
Intrinsic- span the bilayer (carrier channel enzymes)
Function of channel proteins
Form tubes that fill with water- water soluble ions can diffuse
Function of carrier proteins
Binds with larger molecules (glucose,amino acids) and changes shape to transport them to the other side
Role of glycoproteins
Cell surface receptors (for hormones and neurotransmitters)
Recognition sites (for lymphocytes)
Role of glycolipids
Cell surface receptor for specific chemicals (identify blood group for proteins)
Attached cells to each other to form tissue
Diffusion
Net movement of molecules from a region of higher concentration to lower concentration, down a concentration gradient
Factors affecting diffusion
Concentration gradient
Surface area
Length/thickness of diffusion pathway
Facilitated diffusion
Passive process that occurs down the concentration gradient
What is needed for facilitated diffusion?
Proteins for the molecule to travel down (so diffusion only occurs at specific points on the plasma membrane
Fick’s Law
Rate of diffusion is directly proportional to:
(Area of diffusion surface x Concentration Difference ) / Thickness of surface
Similarities of simple and facilitated diffusion
Passive process
Occurs down the concentration gradient
Differences between simple and facilitated diffusion
SD: for small non-polar molecules
FD: for all other molecules
SD: occurs across phospholipid bilayer
FD: occurs across intrinsic proteins