Cell Membraines (Chapter 4) Flashcards

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1
Q

What do membranes do?

A

Control what passed through them

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2
Q

Are membranes partially permeable?

A

Yes

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3
Q

List the three SIMPLE ways substances can move across a membrane?

A

Osmosis

Diffusion

Active transport

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4
Q

What molecules form a continuous bilayer?

A

Phospholipids

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5
Q

Why is the cell membrane model called a fluid mosaic model?

A

Phospholipids are constantly moving and it looks like a bit like a mosaic

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6
Q

What is cholesterols role in the bilayer?

A

Binds to the phospholipid tails causing them to pack more closely- restricting movement making it more rigid

Helps keep animal cell walls more rigid/ and support eg. Red blood cells

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7
Q

What types of proteins are present in the bilayer?

A

Channel proteins

Carrier proteins

Receptor proteins

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8
Q

What are glycoproteins?

A

Proteins which have a polysaccharide chain attached to it

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9
Q

What are glycolipids?

A

Lipids which have a polysaccharide chain attached to it

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10
Q

Can proteins move sideways and also be fixed in position in the bilayer?

A

Yes

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11
Q

In a phospholipid what is the head?

A

Hydrophilic

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12
Q

In a phospholipid what is the tail?

A

Hydrophobic

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13
Q

How is the phospholipid bilayer arranged?

A

Phospholipid heads face outwards and tails inwards

Centre of the bilayer is hydrophobic- membrane does not allow water soluble substances in

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14
Q

Which required practical investigates the permeability of cell membranes?

A

Beetroot cylinders- pigment leakage

Investigate temperature, concentration etc ………

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15
Q

What happens to the permeability of the cell membrane in temperatures below 0°c?

A

HIGHLY PERMEABLE

Phospholipids do not have much energy so don’t move much
Phospholipids packed closer together

Channel and carrier proteins deform
Ice crystals can pierce membrane

Increases permeability

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16
Q

What happens to the permeability of the cell membrane between 0°c & 45°c?

A

Phospholipids can move around and aren’t tightly packed together

MEMBRANE IS PARTIALLY PERMEABLE

As temperature increases phospholipids move more which increases permeability

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17
Q

What happens to the permeability of the membrane at temperatures above 45°c?

A

Phospholipids start to melt

BECOMES MORE PERMEABLE

Water inside cell expands putting pressure on membrane
Channel and carrier proteins deform- cannot control entry and exit

18
Q

Define diffusion

A

Diffusion is the net movement of particles from an area of higher concentration to an area of lower concentration.

19
Q

Can molecules diffuse in both directions?

A

Yes
But the net movement will be to the area of lower concentration. This continues until particles are evenly distributed throughout the liquid or gas.

20
Q

Is diffusion passive?

A

Yes it does not require metabolic energy

(Requires kinetic energy)

21
Q

What is simple diffusion?

A

When molecules diffuse directly through a cell membrane

22
Q

What is facilitated diffusion?

A

Where large or charged molecules, diffuse through carrier or channel proteins in the membrane.

23
Q

Is facilitated diffusion passive?

A

Yes it does not require metabolic energy

(Requires kinetic energy)

24
Q

What do carrier proteins do?

A

Move large molecules across membranes

25
Q

How do carrier proteins work?

A

Large molecule attaches

Protein changes shape

Releases the molecule on the other side of the

26
Q

What do channel proteins do?

A

Allows charged particles to diffuse through the membrane

27
Q

What are the three factors that affect the rate of simple diffusion.

A

The concentration gradient

Thickness of the exchange surface

The surface area

28
Q

How do microvilli increase the surface area for faster diffusion?

A

Large surface area- can increase it by 600 times

29
Q

What are the two factors that affect the rate of facilitated diffusion?

A

Concentration gradient

Number of channel or carrier proteins

30
Q

Define osmosis

A

Osmosis is the diffusion of water molecules across a partially permeable membrane, from an area of higher water potential to an area of lower water potential

31
Q

What is water potential?

A

Water potential is the likelihood of water molecules to diffuse in and out of a solution

32
Q

Does pure water have a high water potential?

A

Yes the highest

All solutions have a lower one than water

33
Q

Define isotonic

A

When two solutions have the same water potential

34
Q

List the three factors which effect the rate of osmosis

A

Water potential gradient

Thickness of exchange surface

Surface area of the exchange surface

35
Q

What is the required practical linked to water potential.

A

Using potato cylinders

5 serial dilutions using sucrose and water

Measure mass change %

36
Q

What is active transport?

A

Active transport uses energy to move molecules and ions across membranes usually against a concentration gradient

37
Q

Which protein is usually involved in active transport?

A

Carrier proteins

38
Q

What are the two main differences between active transport and facilitated diffusion?

A

Active transport usually moves molecules form a low to high concentration, in facilitated diffusion they move from a high to low concentration

Active transport requires metabolic energy (ATP) facilitated diffusion does not

39
Q

How does ATP release energy?

A

Undergoes hydrolysis splitting it into ADP and Pi (inorganic phosphate)

This releases energy

40
Q

What is a co-transporter?

A

A type of carrier proteins which binds to two molecules at a time

41
Q

How does co transport work?

A

Concentration gradient of one of the molecules is used to move the other molecule against its own concentration gradient

42
Q

Explain the 4 steps of co-transport of glucose in the ileum of the small intestine?

A

Sodium ions actively transported out of the epithelial cell into the blood via sodium-potassium pump, this creates a concentration gradient of sodium ions.

This causes sodium ions to diffuse from the lumen of ileum into epithelial cell, down their concentration gradient. Via sodium-glucose co-transporter proteins.

The co-transporter carries glucose into the cell with sodium- glucose concentration inside cell increases.

Glucose diffuses out of the cell into the blood, down its concentration gradient through a protein channel via facilitated diffusion .