Cell mediated immunity Flashcards
how is the production of t cells stimulated?
-its stimulated by the bodies own cells that have been changed due to the presence of non self material
what is the name given to body cells that have been changed due to the presence of non self material?
-antigen presenting cells
what are 3 examples of antigen presenting cells?
-phagocytes that have engulfed a pathogen and have some of its antigens on its membrane
-any type of body cell that has been infected by a virus because some of the antigens will be on its membrane
-cancer cells as they too have antigens on their surface
can viruses live on their own?
-no they need a host cell
what is the process of the production of a range of t cells in cell mediated immunity?
-antigen presenting cell is detected by t lymphocyte
-receptor of specific t lymphocyte is a complementary fit into the viral antigen on the cell surface membrane of the infected antigen presenting cell
-sensitised t lymphocyte divides rapidly by mitosis to form a clone
-the clone then develops into killer t cells, helper t cells, suppressor t cells and memory t cells
what is the job of killer t cells?
-destroy infected cells by attaching to the antigens on the membrane on these infected cells byt destroying them by direct enzyme action