Cell Division [Mitosis] Flashcards

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1
Q

What is the main purpose of mitosis?

A

Growth & Repair

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2
Q

What can mitosis produce from a single parent cell?

A

Two genetically identical daughter cells (single haploid cell (n) or diploid cell (2n) divides into two haploid or diploid daughter cells that are same as parent.)

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3
Q

In what type of cells does mitosis occur? What does it mean?

A

Somatic cells, meaning all cells in the body except for the reproductive cells

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4
Q

Is there a reduction in the number of chromosomes during mitosis?

A

No

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5
Q

Why is mitosis important?

A
  • Growth & development of multicellular organisms
  • Repair & maintenance of damaged tissues (cut/injury)
  • Asexual Reproduction of some organisms
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6
Q

What happens during G1 Phase in mitosis interphase?

A
  • Cell size doubles due to active metabolic activity
  • Replication of organelles
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7
Q

What happens during S-Phase in mitosis interphase?

A
  • DNA replication
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8
Q

What happens during G2 Phase in mitosis interphase?

A
  • Enzymes for cell division are produced
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9
Q

What are the 4 main phases of mitosis?

A

PMAT: Prophase, Metaphase, Anaphase, Telophase

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10
Q

What happens during mitosis prophase?

A
  • Chromosomes condenses (2 sister chromatids, held together at the centromere)
  • Mitotic spindle begins to form from the centrioles as cytoskeleton disassemble
  • centrioles migrate to opposite poles
  • Nucleolus breaks down
  • Chromosomes kinetochore attach to microtubules from each pole
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11
Q

What happens in mitosis metaphase?

A
  • All chromosomes align at the metaphase plate (center of the nucleus)
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12
Q

What happens in mitosis anaphase?

A
  • The chromosomes break apart
  • Sister chromatids move to the opposite ends of the cell
  • Microtubules not attached will elongate and push apart, separating the poles and making the cell longer.
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13
Q

What happens in mitosis telophase?

A
  • Cleavage furrow develops, made from contractile ring
  • Chromosomes decondense and return to their ‘stringy’ form
  • Two new nuclei forms
  • Nuclear membranes and nucleoli reappear.
  • Spindle apparatus breaks down to its building blocks
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14
Q

What happens to plant cells in mitosis telophase?

A
  • Vesicles form an expanding membrane partition (cell plate)
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15
Q

What happens in mitosis cytokinesis?

A
  • Division of cytoplasm
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16
Q

What is the shortest phase?

A

Metaphase

17
Q

Why are checkpoints established during the cell cycle?

A
  • Ensures the process is occurring accurately
  • Prevents unregulated cell division, causes cancer (forms a lump)
18
Q

Where are the cell division checkpoints located and what are their main function?

A
  1. G1/S Checkpoint - tells whether cell cycle continues or stops
  2. G2/M Checkpoint - allows mitosis
  3. Spindle Checkpoint - ensures that all chromosomes have attached to a spindle
19
Q

What are the contributing factors in cell cycle?

A
  • Growth factors
  • Size of cell
  • Nutritional state of cell
20
Q

How long does mitosis typically take?

A

24 hours

21
Q

What happens to cells that do not divide?

A
  1. Die
  2. Take a specialized role (brain neuron)