Cell Division, Chromosome Segregation & Genetic Varieation Flashcards

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0
Q

List the four stages of the eukaryotic cell cycle.

A

1) G1 phase (gap 1)
2) S phase (synthesis)
3) G2 phase (gap 2)

These are collectively known as interphase. Followed by:
4) M phase

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1
Q

What is mitotic cell division?

A

Chromosomes are replicated & then divided to form two identical daughter cells.

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2
Q

Describe the interphase of the eukaryotic cell cycle.

A

The cells grows during G1, the first gap phase. Replication of chromosomes occurs during S phase, then prepares for division during G2 (gap 2).

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3
Q

What two processes occur during M phase of the cell cycle?

A

Mitosis & cytokinesis.

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4
Q

Define cytokinesis.

A

The process of the cytoplasm dividing after mitosis, separating the cell into two daughter cells. Final stage of the cell cycle.

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5
Q

What are the four stages of mitosis?

A

1) prophase
2) metaphase
3) anaphase
4) telophase

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6
Q

What are chromatids?

A

Chromosomes replicate during the interphase of the cell cycle to form sister pairs of chromatids.

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7
Q

What occurs during the prophase of mitosis?

A

Sister pairs of chromatids become condensed enough to be visible under a light microscope. Nuclear envelope begins to break down.

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8
Q

What occurs during metaphase of mitosis?

A

Chromosomes attach to mitotic spindle fibres and line up long the equator of the cell.

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9
Q

What occurs during anaphase in mitosis?

A

Spindle Microtubules shorten, pulling chromatids a parting and resulting in equally segregated chromosomes at opposite ends of the cell.

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10
Q

What occurs during telophase of mitosis?

A

New nuclear envelopes develop around the separate chromosomes. This is the end of mitosis and cytokinesis can the occur.

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11
Q

What is meiosis?

A

The cell division which occurs to form gametes containing half the number of chromosomes.

Instead of two diploid cells the division results in four haploid cells.

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12
Q

What are the phases of meiosis?

A
Prophase 1
Metaphase 1
Anaphase 1
Telophase 1
Prophase 2
Metaphase 2
Anaphase 2
Telophase 2
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13
Q

What is recombination or genetic cross over?

A

During meiosis homologous chromosomes are physically paired together in a process known as synapsis.

Matching DNA sequences line up exactly, allowing the swapping of sections of DNA sequence. This is genetic recombination.

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14
Q

What occurs during prophase 1 in meiosis?

A

Homologous chromosomes are physically paired up a the protein complex called synaptonemal complex.

This then dissembles leaving homologues held together by their crossover genes.

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15
Q

What occurs during metaphase 1 of meiosis?

A

Homologous pairs of chromosomes still attached to each other are aligned at the metaphase plate (unlike mitosis where individual duplicates line up instead of pairs).

16
Q

In meiosis, what is independent assortment?

A

The random segregation of chromosomes due to the different orientations of the homologous pairs during metaphase 1.

17
Q

What occurs during anaphase 1 in meiosis?

A

Homologous pairs separate and move to opposite ends of the cell.

This is different to mitosis where individual sister chromatids segregate.

18
Q

what is the difference between a cell undergoing mitosis after telophase and a cell undergoing meiosis after telophase 1?

A

In mitosis the diploid cells are genetically identical. In meiosis genetic recombination and independent assortment have resulted in non identical diploid cells.

19
Q

What results from telophase 1 in meiosis?

A

Two diploid daughter cells, non identical to each other and the parent cell.

20
Q

What occurs during meiosis 2?

A

Chromosomes again align on the metaphase plate (again in random orientations) and the individual sister chromatids finally segregate during anaphase 2.

21
Q

What is the end result of meiosis?

A

Four haploid cells with a single copy of each chromosome.

These contain different genetic combinations from the diploid germ cell as a result of genetic recombination.