cell division, cell diversity and cell differentiation Flashcards
what are the main stages of mitosis
prophase
metaphase
anaphase
telophase
how is the cell cycle regulated
g1/s checkpoint and g2/M checkpoints are the main ones. they prevent uncontrolled division which would lead to tumours and cancer
they repair damage to DNA for example from UV light
they also ensure the cycle cannot be reversed
and the DNA is only duplicated once during each cell cycle
description of prophase
chromosomes replicated now shorten and thicken as the DNA supercoils nuclear envelope breaks down/ centriole in animal cells divides and move to opposite poles. cytoskeleton protein threads form spindle between these centrioles,
descripton of metaphase
pairs of chromatids attach to the spindle threads at the equator region
they attach by their centromeres
description of anaphase
the centromere of each pair of chromatids splits
motor proteins walking along the tubilin threads pull each sister chromatid of a pair in opposite directions, towards opposite poles
because their centromere goes first the chromatid, now called chromosome, assume a V shape
description of telophase
the separated chromosomes reach the poles. a new nuclear envelope forms around each set of chromosomes.
the cell now contains 2 nuclei each genetically identical to each other
stages of cell cycle
M phase-cell- a checkpoint which triggers condensation of chromatin, halfway through the cycle the metaphase checkpoint ensures that the cell is ready to complete mitosis.
g0 phase a resting phase cells may undergo apoptosis cell differentiation or senescence. some types of cells remain in this phase for a very long time or indefinitely
g1 phase- cells grow and increase in size, transcription of genes to make rna occurs. organellses duplicate biosynthesis,
s synthesis phase of interphase- once cell has entered this phase it is committed to completing the cell cycle. DNA replicates. when all chromosomes have been duplicated each one consists of a pair of identical sister chromatids.
g2- special chemicals ensure that the cell is ready for mitosis by stimulating proteins that will be involved in making chromosomes condense and in formation of the spindle. cells grow
what is the function of mitosis
growth, cell replacement and asexual reproduction.