Cell division, Cell diversity and Cell differentiation part 2 Flashcards

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1
Q

Why do Multicellular organisms need differentiation

A
  • In multicellular organisms specialised cells are needed to carry out specific functions, as most of their cells are not in direct contact with the external environment therefore they are needed to carry out functions
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2
Q

Why do single celled organisms not need differentiation

A
  • In single celled organisms each organelle has a specific function, and they are in contact with the external environment this means that they are small and have a large surface area to volume ratio so that oxygen can disuse across their plasma membrane and waste products can diffuse out of the same membrane
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3
Q

How do differentiated cells form

A
  • Multicellular eukaryotic organisms start a life as a single undifferentiated cell called a zygote
  • Zygote – this results from when an ovum is fertilised by a spermatozoon and two haploid nuclei fuse to give a cell with a diploid nucleus
  • Zygote is not specialised and all the genes in the genome are expressed, it is able to divide by mitosis as it is a stem cell, after several mitosis divisions an embryo forms containing many undifferentiated embryonic stem cells
  • Embryonic stem cells differentiate as certain genes are switched off and others expressed
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4
Q

embryonic cells differentiate as certain genes are switched off and other genes are expressed more this is so that

A
  • the proportions of the different organelles differ from those of other cells
  • the shape of the cell changes
  • some contents of the cell change
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5
Q

What do erythrocytes do

A

carry oxygen from the lungs to respiring tissue

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6
Q

How are erythrocytes specialised

A
  1. They are small so therefore have a large surface area to volume ratio this means that lots of oxygen can diffuse into the cell and easily reach all regions
  2. Flexible so have a well-developed cytoskeleton this allows the erythrocytes to change shape so they can twist and turn as they travel through narrow capillaries
  3. Most organelles are lost a differentiation – have no nucleus, mitochondria or ER, and little cytoplasm – therefore they can have a large amount of haemoglobin
  4. Haemoglobin is synthesised within immature erythrocytes while they still have a nucleus, ribosomes and endoplasmic reticulum
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7
Q

What do neutrophils do

A

ingest invading pathogens

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8
Q

How are neutrophils specialised

A
  1. Twice the size of erythrocytes
  2. Contain a multilobed nucleus
  3. Attracted to and travel towards infection sites by chemotaxis
  4. Function is to ingest bacteria and some fungi by phagocytosis
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9
Q

How are spermatozoa specialised

A
  1. Many mitochondria to carry out aerobic respiration allowing the undulipodium to move and propel the cell towards the ovum
  2. Spermatozoa are small, long and thin so they can move easily
  3. Once it reaches an ovum enzymes are released from the acrosome these digest the outer protective layer which covers the ovum and allows the sperm head to enter the ovum
  4. Head contains haploid male gamete nucleus and very little cytoplasm
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10
Q

How are epithelia cells specialised

A
  • Squamous epithelial cells are flattened in shape in order to increase surface area
  • Many of the cells have cilia
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11
Q

How are palisade cells specialised

A
  1. Long an cylindrical – therefore they are closely packed but they have space between them so that the air can circulate and carbon dioxide can diffuse into cells
  2. Large vacuole so that chloroplasts are near to the periphery of the cell this reduces the diffusion distance for carbon dioxide
  3. Contain chloroplasts
  4. Contain cytoskeleton threads and motor proteins, these move the chloroplasts nearer to the upper surface of the leaf when there is low sunlight intensity but down the leaf when there is high sunlight intensity
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12
Q

How are guard cells specialised

A
  1. Light energy used to produce ATP
  2. ATP transports potassium ions from surrounding epidermal cells into the guard cells by active transport and lowers the water potential
  3. Water enters the guard cells from neighbouring epidermal cells by osmosis
  4. Guard cells swell but at tips the cellulose cell wall is more flexible and is more rigid when it is thicker the tips bulge and the gap between them enlarges
  5. As the stomata open air can enter the spaces within the layer of cells beneath the palisade cells
  6. Gaseous exchange occurs and carbon dioxide will diffuse into the palisade cells – they use this for photosynthesis and this will maintain a steep concentration gradient
  7. Oxygen produced during photosynthesis can diffuse out of the palisade cells into the air spaces and out through open stomata
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13
Q

How are root hair cells specialised

A
  1. Hair like projection increases surface area for absorption of important things such as water and mineral ions as well as nitrates
  2. Mineral ions are actively transported lowering the water potential then causing the water to follow into them by osmosis down the water potential gradient
  3. Root hair cells have special carrier proteins in the plasma membrane carry out active transport
  4. The cells ATP which is needed for active transport
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14
Q

What are the four main tissue types

A
  • epithelial
  • connective tissue
  • muscle tissue
  • nervous tissue
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15
Q

What is the role of connective tissue

A

hold structures together and provide support

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16
Q

what is the role of muscle tissue

A

made out of cells that are specialised to contract and cause movement

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17
Q

what is the role of nervous tissue

A

made of cells specialised to conduct electrical impulses

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18
Q

what is the role of epithelial tissue

A

lining tissue

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19
Q

what is tissue

A

a groups of cells that work together to perform a specific function

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20
Q

How is epithelial tissue specialised

A
  • Covers surfaces of the body
  • Cells are close together and form continuous sheets
  • No blood vessels, but they receive nutrients by diffusion from tissue fluid in the underlying connective tissue
  • Have smooth surfaces but some have cilia or microvilli
  • Have short cell cycles and divide up to two or three times a day to replace worn or damaged tissue
  • Functions – protection, absorption, filtration, excretion, and secretion
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21
Q

How is connective tissue specialised

A
  • Widely distributed in the body. Consists of non-living extracellular matrix containing proteins and polysaccharides which separates the living cells within the tissues and enables it to withstand weight
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22
Q

How is cartilage cells specialised

A
  • Immature cells in cartilage are called chondroblasts, they divide by mitosis and secrete the extracellular matrix. Once the matrix has been synthesised the chrondroblasts have become mature, less active chondrocytes maintain the matrix.
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23
Q

what are the three type of cartilage

A

hyaline, fibrous, elastic

24
Q

What does hyaline cartilage do

A

forms embryonic skeleton, covers the end of long bones in adults, joins ribs to the sternum and found in the nose, trachea and larynx

25
Q

What does fibrous cartilage do

A

occurs in discs between vertebrae in the backbone and in the knee joint

26
Q

what does elastic cartilage do

A

makes up the outer ear and epiglottis

27
Q

How is muscle tissue specialised

A
  • Called fibres and are elongated. They contain special organelles called myofilaments which are made of proteins actin and myosin these allow the muscle tissue to contract
28
Q

What is the functions of muscle tissue

A
  • Skeletal muscles are packaged by connective tissue sheets and are joined to bones by tendons these contract and enables movement
  • Cardiac muscles cause the heart to contract and pump blood around the body
  • Smooth muscle occurs in walls of intestines moving substances along the tracks
29
Q

What is an organ

A

A collection of tissues working together to perform the same function

30
Q

What is an organ system

A

a number of organs working together to carry out an overall life function

31
Q

Organs and tissues involved and example of life processes carried out: Digestive system

A

Oesophagus – stomach, intestines, plus associated glands the liver and pancreas
Nutrition to provide ATP for growth and repair

32
Q

Organs and tissues involved and example of life processes carried out: Circulatory system

A
  • heart and blood vessels

- transport to and from cells

33
Q

Organs and tissues involved and example of life processes carried out: Respiratory system

A
  • airways, lungs, diaphragm and intercostal muscles

- gaseous exchange

34
Q

Organs and tissues involved and example of life processes carried out: Urinary system

A
  • Kidneys ureter and Bladder

- excretion and osmoregulation

35
Q

Organs and tissues involved and example of life processes carried out: Integumentary system

A
  • skin hair nails

- waterproofing, protection, temperature regulation

36
Q

Organs and tissues involved and example of life processes carried out: Musculo-skeletal system

A
  • skeleton and skeletal muscles

- support protection and movement

37
Q

Organs and tissues involved and example of life processes carried out: immune system

A
  • bone marrow, thymus glands, skin, stomach acid and blood

- protection against pathogens

38
Q

Organs and tissues involved and example of life processes carried out: nervous system

A
  • brain spinal cord and nerves

- communication control and co-ordination

39
Q

Organs and tissues involved and example of life processes carried out: endocrine system

A
  • glands that make hormones

- communication, control, and co-ordination

40
Q

Organs and tissues involved and example of life processes carried out: reproductive system

A
  • testes, penis, ovaries, uterus, vagina

- reproduction

41
Q

Organs and tissues involved and example of life processes carried out: lymph system

A
  • lymph nodes

- transports fluid back to the circulatory system and important in resisting infections

42
Q

What is the epidermal tissue

A
  • equivalent to epithelial tissue
  • flattened cells apart from guard cells
  • lacks chloroplasts
  • forms a protective layer covering leaves, stems and roots
  • some have a waxy cuticle - reduces water loss
43
Q

Describe vascular tissue

A
  • concerned with transport
  • xylem and phloem are the two types
  • xylem carries mineral ions and water
  • phloem sieve tubes transfer the products of photosynthesis in solution from leaves, to parts of the plant that do not photosynthesis
44
Q

describe meristematic cells

A
  • contains stem cells
  • where other cells are differentiated from
  • found at roots and shoot tips in the cambium of vascular tissues
  • have thin walls containing little cellulose
  • no chloroplasts
  • large vacuole
  • can divide by mitosis and differentiate into other types of cells
45
Q

How do xylem and phloem derive from meristems

A

xylem - lignin is deposited in their cells to reinforce and waterproof them but this kills the cells, the ends of the cell break down so that the xylem forms a continuous column with a wide lumen so that water can flow through it
phloem - sieve tubes lose there organelles and sieve plates develop between them, companion cells retain their organelles and continue metabolic functions to provide ATP for active loading of sugars into sieve tubes

46
Q

What are the plant organs

A
  • leaf, root, stem, flower
47
Q

What is the function of the leaf and flower

A
  • photosynthesis

- sexual reproduction

48
Q

what is the function of the root

A
  • anchorage in soil
  • absorption of mineral ions and water
  • storage
49
Q

What is the function of the stem

A
  • support
  • holds leaves up so that they are exposed to more sunlight
  • transportation of water and minerals
  • transportation of products and photosynthesis
  • storage of products of photosynthesis
50
Q

What are stem cells

A
  • are undifferentiated cells capable of becoming any type of cell in the organism
  • described as pluripotent
  • able to express all their genes
  • can divide by mitosis and provide more cells that can then differentiate into specialised cells for growth and tissue repair
51
Q

What are the sources of stem cells

A
  • embryonic stem cells
  • stem cells in umbilical cord blood
  • adult stem cells - found in developed tissues such as blood brain muscle bone act as a repair system as they are a renewing source of undifferentiated cells
  • induced in pluripotent stem cells which are developed in labs, reprogramming differentiated cells to switch on key genes and become undifferentiated
52
Q

What are the potential uses for stem cells in biology

A
  • bone marrow transplants
  • drug research
  • developmental biology
53
Q

Describe bone marrow transplants

A
  • already used to treat diseases of the blood and immune system
  • restore the patients blood system after treatment for specific types of cancer - patient bone marrow obtained before treatment, stored then put back after treatment
54
Q

Describe drug research

A
  • stem cells can be developed into types of human tissue so drugs can be tested on them first
55
Q

developmental biology

A
  • study how cells develop to make particular types of cells and learn how each cell type function and what goes wrong when they are diseased
  • extend the capacity that embryos have for growth and tissue repair into later life
56
Q

what else has stem cells been used to treat

A
  • mice with type 1 diabetes - developing a treatment for humans with type one diabetes
  • bone marrow - treat liver disease as cells can be made into liver cells
  • nerve tissue could be used to treat Alzheimer’s and Parkinson’s
  • populate a bioscaffold of an organ and then directed to develop and grow into specific organs for transplanting this is called regenerative medicine same tissue type so no need for immunosuppressant drugs
  • eventually be sued to treat many conditions