cell division and specialisation Flashcards
what are the 3 functions of mitosis
- growth of multicellular organisms
- replacement of cells and repair of tissues
- asexual reproduction
what is asexual reproduction
the production of new individuals of a species by a single parent organism – the offspring are genetically identical to the parent
what are some differences between sexual and asexual reproduction
Asexual:
- one parent
- offspring genetically identical
- no fusion of gametes
- faster creates a large number of offspring quickly
Sexual:
- two parents
- offspring are genetically different
- fusion of gametes
- slower creates a small number of offspring
outline what happens in the G1 phase of interphase
- organelles replicate
- transcription + translation occurs
- size of cell increases
what is checked for in the G1 checkpoint
cell has grown correctly
DNA damage
outline what happens during the S phase of interphase
DNA replicates so that the two daughter cells can each get one set of DNA
what is checked for during the G2 checkpoint
checks that DNA has been replicated correctly
outline what happens during the G2 phase of interphase
energy stores used during ‘S’ phase are replaced, cells continue to carry out transcription and translation.
chromosomes are repaired, cell size increases.
what happens if a cell fails a checkpoint
it leaves the cell cycle and enters G0 phase or undergoes apoptosis.
what happens to fully differentiated cells such as neurons
they can enter G0 permenantly.
what other scenario may a cell enter G0 phase, give an example
Cells can enter G0 temporarily until there is a signal to divide, for example B memory cells are triggered to divide when there is an infection.
why can bacteria not undergo mitosis
because mitosis is the division of the nucleus, bacterial cells do not contain a nucleus. In addition bacterial cells do not form a mitotic spindle
outline the stages of mitosis
prophase - chromosomes condense and become visible, nucleolus dissapears and nuclear membrane breaks down. Pairs of centrioles move to each pole. Proteins form spindle fibres which attach to the centromere of each chromosome.
metaphase - spindle apparatus is compeltely formed, chromasomes are lined up at the equator of the cell
M checkpoint: checks that chromasomes are assembled correctly on the mitotic spindle.
anaphase - centromere divides into two, spindle fibres shorten, which pulls the sister chromatids to opposite poles of the cell
telophase - chromatids reach the poles of the cell. Spindle apparatus breaks down, nuclear membrane reforms. Chromosomes uncoil back to their chromatin state. nucleolus reappears
Outline the process of cytokinesis
- central cell membrane is pulled inwards by the cytoskeleton, creates a furrow which gradually deepens
- membranes fuse to form 2 independant cells
what are 2 differences that occur in cell division in plants
- centrioles do not play a role in forming the spindle apparatus
- during cytokinesis cell membrane cannot form a furrow, instead vesicles from the golgi apparatus form membrane structures down the centre of the cell, these fuse together to form a central cell membrane which divides the cytoplasm into 2. A new cellulose cell wall forms down the centre.