Cell division and Mitosis Flashcards

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1
Q

What is the name for cell division in eukaryotic cells?

A

Mitosis

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2
Q

What are the stages of the cell cycle?

A

Growth 1, synthesis, growth 2, mitosis

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3
Q

Which stages make up interphase?

A

Growth 1, synthesis, growth 2

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4
Q

What occurs during interphase?

A

DNA replication

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5
Q

What are the four stages of mitosis?

A

Prophase, metaphase, anaphase, telophase

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6
Q

What is the role of the spindle fibres in mitosis?

A

Attach to centromeres in the separation of chromatids

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7
Q

What occurs in prophase?

A

Nucleolus and nuclear envelope disappear, chromatin condenses into chromosomes, spindle forms.

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8
Q

What occurs in metaphase?

A

Chromosomes are lined up across the equator of the spindle

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9
Q

what occurs in anaphase?

A

Spindle fibres pull on the centromeeres until they split; spindle pulls sister chromatids to opposite poles of the spindle.

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10
Q

What occurs in telophase?

A

Spindle disintegrates, chromosomes unwind to form chromatin, nucleolus and nuclear envelope reappear

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11
Q

What occurs in cytokinesis?

A

Division of the cytoplasm occurs, producing two new cells

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12
Q

What happens if cell division becomes uncontrolled?

A

Uncontrolled cell division can lead to the formation of tumours and of cancers. Many cancer treatments are directed at controlling the rate of cell division.

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13
Q

What is the name for cell division in prokaryotic cells?

A

Binary fission

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14
Q

What takes place during binary fission?

A
  • Replication of the circular DNA and of plasmids.
  • Division of the cytoplasm to produce two daughter cells, each with a single copy of the circular DNA and a variable number of copies of plasmids.
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15
Q

How do viruses replicate?

A

Being non-living, viruses do not undergo cell division. Following injection of their nucleic acid, the infected host cell replicates the virus particles.

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16
Q

What is the cell cycle?

A

The three stages of cell division/growth:

Interphase, mitosis, cytokinesis

17
Q

What is the function of meiosis?

A

To make gametes (and produce genetic variation)

18
Q

What is a gene?

A

Section of DNA that codes for a protein

19
Q

What is a locus?

A

The position of a gene on chromosome

20
Q

What is an allele?

A

A different form/version of a particular gene

21
Q

What happens in crossing over?

A

Chromosomes twist around each other and exchange equivalent sections of DNA

22
Q

What is the difference between mitosis and meiosis?

A
  • Mitosis produces two identical clone diploid daughter cells
  • Meiosis produces four individual haploid cells
23
Q

What is a mutation?

A

A change to the base sequence of DNA

24
Q

What is a substitution?

A

When one base/nucleotide is replaced with another

25
Q

What is a deletion?

A

When a base/nucleotide is removed from the sequence

26
Q

What is a polyploidy?

A

Where an organism has three or more sets of whole chromosomes instead of the usual two pairs

27
Q

What is non-disjunction?

A

Where there are more or fewer chromosomes on one set e.g. 1 or 3 instead of a pair