Cell division and cellular organisation Flashcards
describe what happens at each stage of the cell cycle
GAP PHASE 1- cell grows, new organelles and proteins are made
G1 CHECKPOINT- the cell checks that the chemicals needed for replication are present and for any damage to the DNA before entering s phase
SYNTHESIS- cell replicates DNA, ready to divide by mitosis
GAP PHASE 2- cell keeps growing and proteins needed for cell division are made
G2 CHECKPOINT- without any damage the cell can enter mitosis
M PHASE- mitosis and cytokinesis followed by metaphase checkpoint
what is the structure of chromosomes in mitosis?
beginning: two strands joined in centre by centromere
the separate strands are called chromatids
Interphase until end: two strands on the same chromosome are called sister chromatids
end:when mitosis is over chromatids ends up as one strand chromosome
describe each stage of mitosis (PMAT)
INTERPHASE- cell is preparing to divide
DNA replicates
cell growth
ATP production is increased
PROPHASE- chromosomes condense and become visible
nuclear envelope breakdown
nucleolus breaks up and disappears
centrioles migrate to opposite poles
mitotic spindle fibres start to form
METAPHASE- spindle fibres attach onto the centromeres
chromosomes are organised across the centre of cell (metaphase plate)
ANAPHASE- spindle fibres contract and pull the sister chromatids apart
cell starts to elongate
TELOPHASE- the chromosomes are no longer visible
nuclear envelope and nucleolus reformes
what happens during cytokinesis?
cytoplasm divides
in animal cell: cleavage furrow forms to divide the cell membrane
in plant cell: the vesicles start to grow until it splits the cell into two
two daughter cells that are genetically identical to original cell
cytokinesis begins in anaphase & ends in telophase
what is meiosis and where does it take place?
allows the production of genetically distinct haploid daughter cells from a diploid parent cell
it occurs in the gametes where two haploid gametes fuse to form one diploid cell
how is meiosis different to mitosis?
mitosis results in 2 identical daughter cells, whereas meiosis results in 4 sex cells
define diploid
a cell containing two complete sets of chromosomes, one from each parent
define haploid
quality of a cell organism having a single set of chromosomes
organisms that reproduce asexually are haploid
define allele
alternative forms of a gene that arise by mutation and are found at the same place on a chromosome
define homologous chromosome
made up of chromosome pairs of approximately the same length, centromere position and staining pattern for genes with the same corresponding loci
define chromatid
one-half of a duplicated chromosome
define sister chromatids
identical copies of the same chromosome formed by DNA replication
attached to each other by a centromere
describe each stage of meiosis
PROPHASE 1- chromosomes condense
begin to pair up
nuclear envelope breakdown
centrioles move to opposite poles
crossing over occurs
METAPHASE 1- pairs of homologous chromosomes line up at the centre
independent assortment occurs
ANAPHASE 1- spindle fibres contract and homologous chromosomes are pulled apart
TELOPHASE 1- nuclear envelope reforms
CYTOKINESIS- two haploid cells are produced
METAPHASE 2- chromosomes line up across the centre
more independent assortment
ANAPHASE 2- spindle fibres contract
sister chromatids pull apart
centromeres splits
TELOPHASE 2- nuclear envelope reforms
CYTOKINESIS- four haploid daughter cells are produced
name three things in meiosis that leads to increased variation
recombination of parental genes when haploid cells fuse during fertilisation
independent assortment of chromosomes during metaphase 1&2
crossing over occurs during meiosis 1 resulting in chromosomes containing a different combination of alleles
what is a tissue?
a group of cells that are specialised to work together to carry out a particular function