cell division Flashcards
chap 6
What is G0? Why might a cell enter G0?
The resting phase, in which the cell leaves the cycle temporarily or permanently
When a cell is specialized it no longer needs to divide, hence entering G0
Which cells DON’T divide?
DNA damaged cells and senescent cells
What happens at each checkpoint of the cell cycle? (4, 3, 2)
G1 checkpoint checks for:
cell size, nutrients, growth factors, DNA damage
G2 checkpoint checks for:
cell size, DNA replication, DNA error
Spindle assembly checkpoint checks for:
all chromosomes attached to spindles and being aligned
What happens at G1 phase? (3)
- proteins synthesised
- organelles replicated
- cell enlarges
What happens at synthesis phase?
DNA replicated
What happens at G2 phase? (3)
- energy stores are increased
- DNA checked for errors
- cell enlarges
True or false- chromatids are singular structures of DNA and chromosomes are the X ones
False- chromatids and chromosomes are the same thing! X pairs are typically called sister chromatids and when they split into singular structures they are then chromosomes
What is the role of the centromere in mitosis? (3)
- holds chromatids together
- attaches chromatids to spindle fibres
- allows chromatids to be separated
MITOSIS: Prophase (3)
- chromatins condense to form chromosomes/chromatids
- nuclear envelope breaks down
- spindle fibres form at poles
MITOSIS: Metaphase
chromosomes lined up at metaphase plate (equator)
MITOSIS: Anaphase (2)
- centromeres divide
- spindle fibres contract to separate sister chromatids
MITOSIS: Telophase (3)
-chromatids/chromosomes reach poles and coil
- nuclear envelope reforms
- nucleolus formed
MEIOSIS I: Prophase I
Chromosomes pair up into BIVALENTS + CROSS OVER
MEIOSIS I: Metaphase I
Homologous pairs (4 chromatids) line up via INDEPENDENT ASSORTMENT
MEIOSIS I: Anaphase I
Chromosomes are pulled to poles + chromatids become RECOMBINANT (as DNA breaks off and rejoins at CHIASMATA)