Cell division Flashcards
what are the two phases in the cell cycle
interphase and mitotic phase
what are three stages in interphase
G1
S
G2
explain what happens in G1
it is the first grow phase when proteins from which organelles are synthesised are produced and organelles replicate, the cell increases in size
explain what happens in S
this is the synthesis phase, where DNA is replicated in the nucleus
explain what happens during G2
it is the second growth phase, the cell continues to increase in size, energy stores are increased
how is the cell cycle regulated
by having checkpoints
G1checkpoint - it is at the end of G1 phase before the entry to S phase. it checks that the chemicals needed for replication are present and any damage in the DNA
G2 checkpoint - at the end of G2 phase before the entry to mitotic phase, it checks whether all the dna has been replicated without damage
what are the two stages in the mitotic phase
mitosis- the nucleus divides
cytokinesis- cytoplasms divides and two cells produced
what is G0
it is the name given to the phase when the cell leaves the cell cycle either temporarily or permanently, reasons for this could be:
- differentiation
- the dna may be damaged
name the stages of mitosis
Prophase
Metaphase
Anaphase
Telophase
define chromatids
two identical copies of DNA (a chromosome) held together by a centromere
why is mitosis needed
- growth of multicellular organisms
-repairing damage tissues - method of asexual reproduction for some plants, fungi and animals
what happens during prophase
- chromosomes condens
- nucleolus disappears
- two bundles of protein called centrioles migrate to opposite poles of the cell, forming a network of protein fibres called a spindle
- nuclear membrane disappears
what happens in metaphase
- chromosomes become attached the spindle by their centromere and move to form a line along the centre of the cell, called the metaphase plate
- during metaphase their is a checkpoint called spindle assembly checkpoint, this checks all chromosomes are attached to spindles and have aligned
what happens during anaphase
- the centromeres divide, separating each pair of sister chromatids
- the spindles shorten so each chromatid is pulled to opposite poles of the cell
- the v shape of the chromatids moving towards the poles is a result of them being pulled by their centromeres first
what happens in telophase
- chromatids have reached their poles, the uncoil and are now called chromosomes
- a nuclear envelope forms around each group of chromosomes so there is two nuclei in the cell