Cell Division Flashcards
One Chromosome
Coiled DNA wrapped around Histone proteins
Centromere: repeated sequences
Duplicated chromosome: 2 neeed for mitosis (sister chromatid)
Interphase (1)
Biomoloecules produced: Nucleic acid (DNA and RNA), proteins, carbs
Preparation for mitosis: duplicated chromosomes DNA, organelles replicated, lots of ATP
Centrioles duplicated and spindle fibres form
Prophase (2)
Nuclear membrane begins to break down
Chromosomes (with pairs of sister chromosomes) begin to condense,
2 centrioles migrate to opposite poles of cell
Spindle fibres form to extend centrioles
Metaphase (3)
Chromosomes consisting of pair of sister chromatids meet in the middle
Spindle fibres from opposite poles attach to the sides of the centromere
Anaphase
Sister chromatids pulled apart by spindle fibres to become daughter chromosomes (single leaf)
Telophase
Spindle fibres disappear
Nuclear membrane form around 2 nuclei
Cleavage furrow then separate
Haploid and diploid cells
Somatic vs Gametes
N=4 one set of chromosomes in the nucleus of cell
2n = 4 2 sets…
Somatic: not gametes, mitosis
Gamete: meiosis
Functions of Mitosis and Cancer
Function of mitosis: growth and repair (not reproduction in single-cell organisms)
Cancer: mitosis is too fast/often
Genetic mutations is uncontrolled, forming a mass (tumor) benign or invade or cells (malignant)
Carcinogens
Meiosis
-halves chromosomal number (2n - n)
4 daughter nuclei (not 2)
-genetic variation (not clones)