Cell division Flashcards
what are the two types of nuclear divisions
- mitosis
- meiosis
define gene
gene is a specific sequence of nucleotides along a DNA molecule that codes for a specific sequence of amino acids that make up a polypeptide chain.
where is a gene found
locus (s) - specific location on a chromosome
after DNA replication…. what is formed?
2 genetically identical DNA molecules joined at the centromere
when chromotin condenses -> visible DNA molecule = sister chromatid
outline how cancer is caused
what is the function of tumor suppressor genes?
codes for proteins that inhibit normal cell growth by preventing stimulating activity of cellular proto-oncogenes or oncogenes
e.g :
1. as components in the cell-signalling pathwas that inhibit the cell cycle
2. activate DNA repair proteins that repaur damaged DNA, preventing accumulation of cancer-causing mutations
3. activate proteins that trigger apoptosis of irreparably-damaged cells