Cell Division Flashcards
What happen during interphase?
Main : Replication of DNA Side: - Cell builds up a large store of energy - Cell Manufacture proteins - Cell synthesizes organelles
What happen during mitotic prophase / meiosis prophase II
Chromatin condenses to form chromosomes (nucleolus disappear)
Nuclear envelope breaks down
Centrioles move to opposite ends of the cell
Mircrotubules/Spindle fibres attach to centromerre of chromosomes and move them towards centre of cell
What happen during mitotic metaphase / meiosis metaphase II?
Chromosomes line up at spindle equator
What happen during mitotic anaphase/ meiosis II anaphase?
Sister chromatids of each chromosome are pulled apart by spindle fibre shortening
separated sister chromatids of each chromosomes move to opposite poles of spindle
What happen during mitotic telophase/ meiosis telophase II
- Nucleolus reappears
- Nuclear envelope reforms to form 2 daughter nuclei
- Chromosomes uncoil to form long and thin chromatin threads
- Spindle fibers disintegrate
What happen during cytokinesis?
In animals, a cleavage furrow forms and pinches cell into two, producing two daughter cells
In plants, a cell plate forms, growing outwards until it touches parental walls forming two separate cells
What are homologous chromosomes?
Any two chromosomes that determine same characteristics
All individuals of same species have same ___ and ____ of chromsomes
number
type
Do homologous chromosomes need to be identical?
No, they can contain different allele for same gene
Why is mitosis important
It is to produce genetically identical cells for:
- Growth of an organism (by increasing no. of cells)
- Repair of worn- out parts of tissue, replacing dead/damaged cells
- Asexual repro
Why must DNA replication and mitosis be precisely controlled?
– To ensure all daughters
cells are genetically stable
- If an error occur during replication, new DNA strand formed would be different from original (gene mutation)
- gene mutation passed on to daughter cell
- as genes are responsible for normal cell growth and division, some forms of gene mutation may lead to uncontrolled division of cells-cancer
Causes of cancer (5)
Age
Chemicals - carcinogen chemicals (ef tar in cigerrate smoke)
Radiation
Viruses
Genetic Factor - eg breast cancer runs in family
Importance of producing haploid gametes during meiosis during sexual repro
Produce haploid gametes which fuse tgt during fertilisation to produce diploid cells
This ensures number of chromosomes in an organism is maintained through successive generation
What happen during meiosis 1 prophase
- Chromatin thread condenses to form distinct chromosomes
- nucleolus disappears
- nuclear envelope disintegrate
- centrioles move to opposite ends of cells and short microtubules develop from them to form meiotic spindle
- Synapsis occur, homologous chromosomes pair up, forming bibalent
- crossing over between chromatids of homologous chromosome occurs at chiasma
What happen during meiosis 1 metaphase
- Bivalents arrange themselves at equator of spindle, aided by spindle fibers
- arrangement of chromosomes of each bivalent at spindle equator is completely independent of the orientation of other bivalents, resulting in indepenedent assortment of chromosomes