Cell Death Pathways (6) Flashcards
1
Q
When does cell death occur?
A
Normal phyisology; removing damaged cells; following tissue injury; unwanted disease; impaired in some disease
2
Q
When is a cell dead?
A
Lost plasma membrane integrity; complete disintegration; corpse/fragments engulfed in vivo
3
Q
Apoptosis
A
Specific morphological features, programmed cell death
4
Q
Necrosis
A
Swelling and rupture of injured cells lacking features of apoptosis or autphagy (regulated
5
Q
Autophagy
A
Cell eating itself, promoting cell survival
6
Q
Cornification
A
Exclusive to the upper layers of the epidermis
7
Q
Inducers of Apoptosis
A
engagement of cell surface receptors; Withdrawal of growth; DNA damage; increasing list of chemical agents
8
Q
Phases of apoptosis
A
Induction, execution and degradation
