CELL CYCLE QUIZ AAAAAA Flashcards

1
Q

2 Reasons for the cell cycle

A
  1. Replace old/damaged cells
  2. Growth/development of organism
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2
Q

Purpose of G1 and its checkpoint

A

A big growth spurt, produces proteins necessary for later steps. It’s checkpoint searches for DNA damage, adequate size.

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3
Q

Purpose of G0

A

branches off of G1
cell exists the cell cycle and stops dividing

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4
Q

Purpose of synthesis

A

DNA replication occurs

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5
Q

Purpose of Gap 2 and its Checkpoint

A

The cell continues to grow and prepares for mitosis. Its checkpoint checks for DNA replication errors back in synthesis before entering mitosis

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6
Q

What is the purpose of mitosis and it’s checkpoint.

A

The cell divides its duplicated chromosomes and cytoplasm. The checkpoint during metaphase makes sure the spindle fibers are correctly attached to chromosomes.

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7
Q

Parts of the cell cycle in order:

A

G1 (with checkpoint)
G0 (optional)
Synthesis
G2 (with checkpoint)
Mitosis

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8
Q

Role of CDK and cyclin

A

Signal timing of each phase and serve as supervisors for various checkpoints.

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9
Q

Role of p53 enzyme

A

Enzyme that stops cell division if DNA is damaged. The cell will either repair itself or if the damage is too severe, trigger the cell to self-destruct (apoptosis)

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10
Q

How do tumors form?

A

Mutated DNA somehow alters CDK-cyclin/p53 and duplicates with genetic errors that lead to uncontrolled cell division, so the cell can’t stop dividing even if there is DNA damage.

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