CELL CYCLE QUIZ AAAAAA Flashcards
2 Reasons for the cell cycle
- Replace old/damaged cells
- Growth/development of organism
Purpose of G1 and its checkpoint
A big growth spurt, produces proteins necessary for later steps. It’s checkpoint searches for DNA damage, adequate size.
Purpose of G0
branches off of G1
cell exists the cell cycle and stops dividing
Purpose of synthesis
DNA replication occurs
Purpose of Gap 2 and its Checkpoint
The cell continues to grow and prepares for mitosis. Its checkpoint checks for DNA replication errors back in synthesis before entering mitosis
What is the purpose of mitosis and it’s checkpoint.
The cell divides its duplicated chromosomes and cytoplasm. The checkpoint during metaphase makes sure the spindle fibers are correctly attached to chromosomes.
Parts of the cell cycle in order:
G1 (with checkpoint)
G0 (optional)
Synthesis
G2 (with checkpoint)
Mitosis
Role of CDK and cyclin
Signal timing of each phase and serve as supervisors for various checkpoints.
Role of p53 enzyme
Enzyme that stops cell division if DNA is damaged. The cell will either repair itself or if the damage is too severe, trigger the cell to self-destruct (apoptosis)
How do tumors form?
Mutated DNA somehow alters CDK-cyclin/p53 and duplicates with genetic errors that lead to uncontrolled cell division, so the cell can’t stop dividing even if there is DNA damage.