cell cycle/mitosis Flashcards

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1
Q

does cell division occur in all multicellular organisms?

A

no because not all multicellular organisms retain the ability to divide

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2
Q

what are the stages of the cell cycle?

A
  • interphase
  • prophase
  • metaphase
  • anaphase
  • telophase (cytokinesis)
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3
Q

what are the three growth stages which occur during interphase?

A
  • gap phase 1
  • synthesis
  • gap phase 2
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4
Q

what happens during gap phase 1?

A

cell grows and duplicates organelles

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5
Q

what happens synthesis?

A

DNA replication

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6
Q

what happens during gap phase 2?

A

cell continues to grow and produces proteins
(ATP content is also increased to produce energy for cell division)
- cell double checks that organelles have been correctly duplicated before moving onto mitosis

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7
Q

what are four stages of mitosis?

A
  • prophase
  • metaphase
  • anaphase
  • telophase
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8
Q

what happens during prophase?

A
  • chromosomes visible (shorten/thicken/ coil)
  • nucleolus disappears
  • nuclear envelope disappears
  • centrioles divide and migrate to opposite poles of cell
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9
Q

what happens during metaphase?

A
  • centrioles produce spindle fibres which attach to centromeres of chromosomes
  • contraction of fibres pulls the chromosomes to equator
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10
Q

what happens during anaphase?

A
  • chromosomes are pulled to opposite poles centromere first
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11
Q

what happens during telophase?

A
  • chromosomes reach poles
  • begin to uncoil and less distinct
  • nuclear envelope develops
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12
Q

what happens during cytokinesis?

A

division of cytoplasm producing two identical cells

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13
Q

why is mitosis important?

A
  • growth
  • repair
  • reproduction
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14
Q

what is the advantage of having offspring genetically identical to parents?

A
  • genetic info of parents has enabled it to survive and reproduce
    therefore offspring with same genetic makeup are likely to survive and reproduce
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15
Q

what is the disadvantage of having offspring genetically identical to parents?

A
  • variation is limited
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16
Q

what is cancer?

A

group of diseases caused by uncontrolled mitosis

17
Q

what can cause uncontrolled mitosis?

A

mutation - mutant cells are structurally and functionally different from normal cells
- any mutant cells which survive have the ability to divide and form clones leading to formation of tumours

18
Q

how does chemotherapy work?

A

use drugs to disrupt cell cycle by preventing DNA replication and inhibiting metaphase (spindle formation)

19
Q

what are disadvantages of chemo?

A
  • affects normal healthy cells but more effective against rapidly dividing cells
  • leads to hair loss because hair-producing cells divide rapidly so vulnerable to damage