Cell Cycle and cell division Flashcards
What is cell cycle?
sequence of events in which a cell duplicates its genome, synthesis other constituents and divides into two daughter cells.
At what rate does the human cell divide?
every 24 hours
( 23 hrs - interphase)
(1 hr - M-phase)
What is interphase?
Phase where the preparation of the cell for division takes place (or) phase between two successive m-phase
What happens in interphase?
cell growth and dna replication
What are the 3 phases of interphase?
G1 PHASE
S PHASE
G2 PHASE
What happens in g1 phase?
Cell grows
remains metabolically active
Synthesis of rna and proteins
preparation for dna replication
what happens in s phase?
DNA synthesis or replication in nucleus.
Amount of DNA doubles
amount of chromosomes remains the same.
Centrioles divides in cytoplasm.
What happens in g2 phase?
preparation for mitosis.
synthesis of rna and proteins.
cell growth.
What is G0 phase?
Cells that do not divide exits g1 phase and enters an inactive phase called quiescent phase. it is metabolically active but divides only if said so.
What is m-phase?
phase where the actual cell division occurs.
Divided into two:
1. karyokinesis
2. cytokinesis
What are the 4 phases of karyokinesis?
- prophase
- metaphase
- anaphase
- telophase
Explain prophase
- chromosomal materials gets condensed into chrmosomes
- Centrosomes moves towards opposite poles and radiate microtubules called the aster along with spindle fiber.
- Nucleolus, nuclear envelop, golgi and er disappears
Explain metaphase.
- complete condensation takes place.
- complete disintegration of nuclear envelop takes place.
- kinetochores get attached to the spindle fibers.
- chromosomes move to the equator or align at the metaphase plate.
Explain anaphase.
- centrioles get split and chromosomes seperate and move towards the poles with its arms trailing behind.
Explain telophase.
- Chromosomes decondenses and loses their individuality.
- nucleolus and nuclear envelop reappears.