cell cycle and cell division Flashcards
how chromosome is formed?
in the nucleus of each cell the DNA molecule is packaged into thread like structure called chromosomes. each chromosome is made up of DNA tightly coiled many time around called histones that support its structure
internal sructure of histone
H2A, H2B, H3, H4
highly alkaline found in eukaryotic cell nuclei that package and order the DNA into structrtural units called_________?
nucleosome
parts of chromosome
telomere
shortarm
centromere
longer arm
sister chromatid
protective caps at the end of DNA molecules that make up our chromosomes
telomere
the region of a chromoses to whichh the microtubules of the spindle attach, via the kinetochore during cell division
centromere
different types of chromosome based on centromere position
metacentric- centromere in the middle of chromosome
submetacentric
acrocentric - chromomere near the end of the chromosomes
telocentric - chromomere at the end
what are the chromosal abnormalities
cru-du-chat syndrome
down syndrome
47, XXY (klinefelter syndrome)
turner syndrome
williams syndrome
is a group of symptoms that result from missing a piece of chromosome
cri-du-chat syndrome
autosomal deletion syndrome caused by a partial deletion of chromose 5 and is characteized by a distinctive, high pitched, catlike cry infancy with growth failure
cri-du-chat syndrome
chromosal condition that is asscociated with intellectual disability, facial appearance and weak muscle tone in infancy
down syndrome
genetic condition in which a huma male has an extra male (Y) chromosome
klinefelter syndrome
occurs when one of the two X chromosome s normally found in women is missing or incomplete
turner syndrome
caused by deletion of additional genetic material near the elastin gene on chromosome 7
william syndrome
what are the alterations of chromoses structures
deletion
duplication
inversion
translocation
occurs when a chromosome fragment lacking a centromere is lost during cell division
deletion
occurs when a fragment becomes attached as an exra segment to a sister chromatid
duplication
occurs when a chromosal fragment reattaches to the original chromosome but in the reverse orientation
inversion
a chromosal fragment joinsa nonhomologous chromosome
translocation
is an orderly set of stages that take place betweemn the time a cell divides and the time the resulting daughter cells also divide
cell cycle