cell cycle and cancer

Question 1

protooncogene example

Answer 1

ras - GTPase

myc - TF

Question 2

tumour suppressor gene example

Answer 2

p53
APC
BRCA1 and 2

Question 3

when is MPF in high conc

Answer 3

in M phase

Question 4

when is there no MPF

Answer 4

interphase

Question 5

when is cyclin broken down completely

Answer 5

start of G1

starts formation at start of G2

Question 6

what does the G2 checkpoint check for

Answer 6

all chormosomes are attached to spindles

Question 7

what does G1 check for

Answer 7

undamaged DNA
cell size
nutrition
appropriate signals
otherwise exit to G0