Cell Communication and Signalling

Question 1

Name the 3 stages of cell communication

Answer 1

1. Receptor Activation
2. Signal Transduction
3. Cellular Response

Question 2

Describe all the stages of cell communication

Answer 2

Signal binds to receptor (receptor activation). The activated receptor stimulates a sequence of cellular changes called a signal transduction pathway (signal transduction). A cellular response is generated

Question 3

Whats the signalling molecule called

Answer 3

Ligand

Question 4

Name the 3 receptor types

Answer 4

1. Enzyme linked receptors
2. G-protein-coupled receptors
3. Ligand gated ion channel

Question 5

Explain what a enzyme linked receptor does

Answer 5

It has a catalytic activity

Question 6

Explain what a G protein coupled receptor does

Answer 6

Interacts with heterotrimeric G proteins to initiate a cellular response

Question 7

Explain what a ligand gated ion channel does

Answer 7

Mediates the entry of specific ions into the cell

Question 8

What disease is associated with diminished levels of apoptosis

Answer 8

Cancer

Question 9

What disease is associated with increased apoptosis

Answer 9

Viral/ neurodegenerative diseases

Question 10

What affect does adrenaline have on glycogen breakdown and glycogen synthesis

Answer 10

Increases breakdown and inhibits synthesis

Question 11

What is cAMP

Answer 11

Secondary messangers

Question 12

Suggests benefits of cAMP

Answer 12

Anplifies the signal and increases the speed of signaling pathways

Question 13

Whats the term for an agent that allows the cell to respond to changes in its environment

Answer 13

Signal

Question 14

The EGF receptor functions as…

Answer 14

a receptor tyrosine kinase, a enzyme linked receptor

Question 15

The estrogen receptor is a cell surface receptor, true/false?

Answer 15

False

Question 16

What stage of cell signaling doesnt occur with the estrogen receptor

Answer 16

Signal transduction