Cell biology part 1 Flashcards

1
Q

Chromosomes as connected by

A

Cohesin and centromere proteins

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2
Q

Chromosomes have two arms..

A

shorter p, longer q

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3
Q

Karyogramm

A

Every chromosome arranged by size

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4
Q

Contraction ring made of .. , helped by

A

actin filaments, myosin II

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5
Q

Outgrowth of new MT from

A

y tubulin ring complex

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6
Q

Inhibits formation of MT (protein)

A

Stathmin

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7
Q

Fragments MT (protein)

A

Katanin

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8
Q

Binds MT to IF (protein)

A

Plectin

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9
Q

Binds MT to other structures

A

TIP

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10
Q

MTOC, with …

A

Microtubule organization center, centrioles

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11
Q

Funtion of MT

A

Cilia, mitotic spindle, shape of cell, cargo

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12
Q

Motorproteins associated with MT

A

Dynein and kinesin

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13
Q

Formation of MT in cilia + other structures

A

9x2 + 2, nexin, central sheth, dynein

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14
Q

Actin filaments or microfilaments made of

A

Polymers of actin filaments

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15
Q

Proteins associated with AF

A

alfa actinin, fimbrin

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16
Q

Inhibits AF polymerisation (protein)

A

Thymosin

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17
Q

Fractures AF (protein)

A

Gelsolin

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18
Q

Stabiliazes AF (protein)

A

Tropomyosin

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19
Q

End of AF (protein)

20
Q

Function of AF

A

Cell cortex, microvilla, movement of cells, contraction ring, muscle with myosin

21
Q

Intermediate filaments are…

A

fibrous proteins, 8 tetramers twisted together

22
Q

Connecting IF to other structures (protein)

23
Q

Making IF more stable (protein)

24
Q

Family of IF (name some)

A

Different endings:

1) Cytokeratins in epithelia
2) Vimentin (supporting tissue)
3) Neurofilaments (nerve cells)
4) Lamins (nuclear envelope)

25
Mechanical connections (names)
macula (Desmosoma), hemidesmosoma, zona adherense
26
Diffusion barriers (name)
Zona occudes (tight junction)
27
Communication junction (name)
nexus (gap junction)
28
Zona adherence made of..
Cadherins, adaptor proteins, AF
29
Desmosoma made of
desmoglein, adaptor pr, IF
30
Hemidesmosomes function
Epithelial cells to lamina basalis
31
Zona occludens (proteins)
ZO1, ZO2, occludin, claudin
32
Transmembrane receptors' tree domanis
Cytoskeleton, transmembrane domain and extracellular domain
33
Extracellular domains have tree categories
Homophilic, heterophilic, "linkers"
34
Ca+ dependent
Cadherins, intergrins, selectin
35
Ca+ independent
Immunoglobin superfamily
36
Cadherin types
E (epithelium) P (placenta) N (neural) M (muscular) R (retinal) VE (vasculat endothelium) K (kindey)
37
Selectin types
L (leucocytes) P (platelets) E (endothelium)
38
Integrins work on
ECM
39
If integrin transfer signals it's by (protein)
Talin (activ and inactiv)
40
Glycocalyx on epithelium, function
MHC (major histocompability complex) - Aid attachment to extracellular matrix - Binding antigens and enzymes to cell surface - Cell-cell recognition and interaction - Protection against bacteria
41
Structures on epithelial cells from top to bottom
zona occlucens, zona adherence, desmosomes, gap junction, hemidesmosomes
42
Function of lamina basalis, type of collagen
inhibit free diffusion, polarity, type 4
43
Layers of basement membrane
lamina rara interna, lamina densa, lamina rara externa, lamina reticularis
44
Microvilla made of
Microfilaments / AF
45
Stereocilia made of
Actin filaments / MF
46
Cilia made of
Microtubules