Cell Bio Quiz 2 Flashcards
Phospholipids are ____________ which means that they are molecules that have both hydrophilic and hydrophobic regions.
amphipathic
The region of a phospholipid molecule that is hydrophilic is characterized by
a phosphate containing group
Phospholipids added to water automatically orient into
bilayers
Phospholipds, cholesterol, and glycolipids share which of the following characteristics? (choose all that apply–the characteristic must be present in all three types of molecules)
all can be found in biologic membranes
are amphipathic
have hydrocarbon tails
have hydrophilic regions
Individual phospholipid molecules are free to migrate laterally within one layer of the phospholipid bilayer.
True
Individual phospholipid molecules often spontaneously flip from one layer of the phospholipid bilayer to the other without the aid of a transporter.
False
Phospholipids with shorter fatty acids tend to be more _______ than phospholipids with longer fatty acids.
Flexible
Consider the phospholipids that compose the biological membranes in arctic fish as opposed to tropical fish. Which of the following is correct about these two groups.
the membranes of the arctic fish would contain more unsaturated fatty acids as compared to the membranes of the tropical fish
New membrane phospholipids are synthesized at:
the cytosolic leaflet of the endoplasmic reticulum
___________ is a transporter that is responsible for the random flip flopping of membrane phospholipids at the endoplasmic reticulum.
Scramblase
Most biological membranes are symmetric, i.e., they have the same phospholipids, proteins, and glycolipids present in both layers of the bilayer.
False
___________ are integral membrane proteins that extend completely through both layers of the phospholipid bilayer.
transmembrane proteins
____________ can be removed from the membrane only by disrupting the membrane with detergents.
integral membrane proteins
The great majority of the membrane-spanning segments of transmembrane proteins extend through the bilayer in the conformation of
alpha helix
Which of the following characterizes the transmembrane spanning region of a single pass polypeptide?
all of the side chains of the amino acids in the transmembrane spanning region are hydrophobic
The PM of animal cells is reinforced by the presence of a meshwork of filamentous proteins known as the _________ and attached to the cytosolic layer of the PM.
cell cortex
Membrane proteins can concentrate in one specific region in a membrane known as a
membrane domain
Which of the following is a mechanism for limiting the migration of membrane proteins and creating membrane domains? (Choose all that apply)
Membrane proteins can be tethered to proteins of the extracellular matrix.
Membrane proteins can be tethered to membrane proteins of adjacent cells.
Membrane proteins may be tethered to proteins of the cell cortex.
Membrane proteins may be confined to one region of the membrane by tight junctions.
The ___________ is a “sugar coating” at the extracellular surface that is responsible for cell protection, lubrication, and cell to cell communication/recognition.
glycocalyx
Which of the following can pass through the phospholipid bilayer of a biological membrane unassisted at a rate fast enough to be biologically relevant? (Choose all that apply)
small, nonpolar solutes
small uncharged, polar solutes
Which of the following is the major cation in the extracellular fluid.
Na+