Cell bio

Question 1

M phase

Answer 1

• consists of mitosis & cytokinesis

Question 2

what phase of cell cycle does transcription occur?

Answer 2

G1

Question 3

coding strand

Answer 3

non-template strand, bc the sequence of mRNA is the same as the non-template strand of DNA

Question 4

one single RNA sequence can make multiple or different RNA molecules

Answer 4

means that the template strand for 1 gene may be the non-template strand for other genes

Question 5

main elements of Pre-inition complex for DNA transcription

Answer 5

RNA 1 2 OR 3

TATA-box binding protein

general transcription factors (TFIIA, TFIIB, TFIID, TFIIF for pol 1) or related proteins for pol 1 & 3

Question 6

G1 checkpoint

Answer 6

Determine appropriate growth conditions (sufficient nutrients, cell size, presence of growth factors, etc.)
Assess level of DNA damage (from ionising radiation or UV)

Question 7

G2 checkpoint

Answer 7

Determine state of pre-mitotic cell (suitable cell size required for successful division)
Identify an replication faults (changes to DNA sequence will distort genetic fidelity in daughter cells)

Question 8

Metaphase checkpoint

Answer 8

Ensure proper spindle assembly and correct attachment to centromeres (prevents non-disjunction events)

Question 9

checkpoints

Answer 9

sensing of internal & external environments (red dot, checkpoints)

primary way to control genetic stability

Question 10

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