Cell and Organelles Flashcards

1
Q

What are we studying when we look at histology?

A

The study of a normal cell

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2
Q

What is the purpose of histopathology?

A

The study of diseased tissues

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3
Q

What is the name of the living components of the cell?

A

Protoplasm

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4
Q

What are the 2 components of the protoplasm?

A

Cytoplasm and the nucleus.

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5
Q

What is included in the cytoplasm?

A

Organelles and inclusions

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6
Q

What are the two types of organelles?

A

Membranous and non-membranous

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7
Q

What are the 7 types of membranous organelles?

A

Plasma membrane, Rough endoplasmic Reticulum, Smooth endoplasmic reticulum, Golgi Apparatus, Endosomes, Lysosomes, and Transport vesicles

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8
Q

What are the 4 types of non-membranous organelles?

A

Microtubules, Filaments, Centrioles, and Ribosomes

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9
Q

What is contained in the nucleus?

A

The genetic information and the machinery for DNA and RNA replication and transcription.

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10
Q

What is included in a non dividing cell?

A

Chromatin, Nucleolus, Nuclear envelope, nucleoplasm

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11
Q

What is the role of the nuclear pores?

A

They are an area where the inner and outer membranes are fused to allow communication between the nucleus and cytoplasm.

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12
Q

What is the role of the chromatin?

A

It is the site for RNA synthesis.

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13
Q

What is the functions of the plasma membrane?

A

It provides a barrier between the cell and the outside environment, as well as in cell recognition and a receptor site for G proteins.

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14
Q

What does it mean if there is a transport protein that uses a coupled transport that is antiport?

A

That there are two proteins that use it and they will travel in opposite directions.

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15
Q

How are transport proteins regulated in neurons?

A

They are regulated by the membrane potential

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16
Q

How are transport proteins regulated in skeletal muscles?

A

The neuromuscular junctions possess ligand-gated ion channels

17
Q

What is vesicular budding?

A

The major mechanism by which particles enter, leave, or move around within the cell.

18
Q

Define Pinocytosis

A

Nonspecific ingestion of fluid and small protein molecules via small vesicles.

19
Q

Define Phagocytosis

A

The uptake of particulate matter

20
Q

Define Receptor mediated endocytosis

A

Low density lipoproteins

21
Q

What are the three types of endocytosis?

A

Pinocytosis, Phagocytosis, and receptor-mediated endocytosis

22
Q

What are the two general pathways of exocytosis

A

Constitutive secretion and Regulated secretion

23
Q

Define Constitutive secretions?

A

Substances that are designated for export are delivered in transport vesicles.

24
Q

Define Regulated Secretion

A

Vesicles that have been stored in the cytoplasm to be released with hormonal or neural stimulus is received.

25
Where is the porin found?
In the outer membrane of the mitochondria.
26
What are the cristae?
Folds in the inner membrane of the mitochondria that form a shelf like projection.
27
What is the role of cardiolipin?
a phospholipid that makes the inner membrane impermeable to ions, electrons, and protons.
28
What are the five main roles of the mitochondria?
Generate ATP, Generate heat in brown fat, Assist in synthesis of certain lipids, TCA cycle enzymes, and they take part in apoptosis.
29
What is the role of the sER?
Synthesis of cholesterol and lipids, in the skeletal muscles it releases calcium
30
What is the role of the rER?
synthesis and modifications of proteins that are to be packaged.
31
What are the two main roles of the golgi apparatus?
Phosphorylation and glycosylation of proteins, and protein sorting
32
What is the role of the lysosomes?
They are responsible for the degradation of certain molecules and phagocytosed material
33
How are lysosomal storage diseases characterized?
As dysfunctional lysosomes that are unable to degrade the contents of their endolysosomes
34
What is the role of peroxisomes?
The catalase present regulate the amount of hydrogen peroxide and thus protect the cell.
35
What are the three groups of the cytoskeleton?
Microtubules, microfilaments, Centrioles
36
What is the role of microtubule associated proteins (MAPs)
Allow for the organelles and other components of the cytoskeleton to bind to the microtubules.
37
What control the cell cycle and help determine when it can move forward?
Cyclin and cyclin dependant kinases